GO Annotations Graph

• Symbol: Ak4
• Name: adenylate kinase 4
• ID: MGI:87979

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004017	adenylate kinase activity	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0019205	nucleobase-containing compound kinase activity	IEA	J:72247
Molecular Function	GO:0004550	nucleoside diphosphate kinase activity	ISO	J:164563
Molecular Function	GO:0004550	nucleoside diphosphate kinase activity	IBA	J:265628
Molecular Function	GO:0046899	nucleoside triphosphate adenylate kinase activity	IEA	J:72245
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016776	phosphotransferase activity, phosphate group as acceptor	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005759	mitochondrial matrix	IDA	J:71059
Cellular Component	GO:0005759	mitochondrial matrix	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Biological Process	GO:0046033	AMP metabolic process	ISO	J:164563
Biological Process	GO:0046033	AMP metabolic process	IBA	J:265628
Biological Process	GO:0046034	ATP metabolic process	ISO	J:164563
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0046039	GTP metabolic process	ISO	J:164563
Biological Process	GO:0006139	nucleobase-containing compound metabolic process	IEA	J:72247
Biological Process	GO:0009142	nucleoside triphosphate biosynthetic process	ISO	J:164563
Biological Process	GO:0009142	nucleoside triphosphate biosynthetic process	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:2001169	regulation of ATP biosynthetic process	ISO	J:164563
Biological Process	GO:0002082	regulation of oxidative phosphorylation	ISO	J:164563