GO Annotations Graph

• Symbol: Prdx3
• Name: peroxiredoxin 3
• ID: MGI:88034

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016209	antioxidant activity	IEA	J:72247
Molecular Function	GO:0016209	antioxidant activity	IEA	J:60000
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:103507
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0004601	peroxidase activity	IEA	J:60000
Molecular Function	GO:0051920	peroxiredoxin activity	IEA	J:72247
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0008379	thioredoxin peroxidase activity	ISO	J:164563
Molecular Function	GO:0008379	thioredoxin peroxidase activity	IBA	J:265628
Molecular Function	GO:0140824	thioredoxin-dependent peroxiredoxin activity	IEA	J:72245
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0045454	cell redox homeostasis	IBA	J:265628
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0034614	cellular response to reactive oxygen species	ISO	J:164563
Biological Process	GO:0033554	cellular response to stress	IBA	J:265628
Biological Process	GO:0042744	hydrogen peroxide catabolic process	ISO	J:164563
Biological Process	GO:0042744	hydrogen peroxide catabolic process	IBA	J:265628
Biological Process	GO:0042744	hydrogen peroxide catabolic process	ISO	J:25560
Biological Process	GO:0001893	maternal placenta development	IMP	J:137348
Biological Process	GO:0007005	mitochondrion organization	ISO	J:164563
Biological Process	GO:0030099	myeloid cell differentiation	IMP	J:36017
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0033673	negative regulation of kinase activity	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0018171	peptidyl-cysteine oxidation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	ISO	J:164563
Biological Process	GO:0042542	response to hydrogen peroxide	ISO	J:164563
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:118595
Biological Process	GO:0006979	response to oxidative stress	ISO	J:164563
Biological Process	GO:0006979	response to oxidative stress	IBA	J:265628
Biological Process	GO:0006979	response to oxidative stress	IMP	J:118595
Biological Process	GO:0006979	response to oxidative stress	IMP	J:137348