GO Annotations Graph

• Symbol: Apoa4
• Name: apolipoprotein A-IV
• ID: MGI:88051

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016209	antioxidant activity	ISO	J:164563
Molecular Function	GO:0120020	cholesterol transfer activity	ISO	J:164563
Molecular Function	GO:0005507	copper ion binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0031210	phosphatidylcholine binding	ISO	J:164563
Molecular Function	GO:0031210	phosphatidylcholine binding	IBA	J:265628
Molecular Function	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity	ISO	J:164563
Molecular Function	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity	IBA	J:265628
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0042627	chylomicron	ISO	J:164563
Cellular Component	GO:0042627	chylomicron	ISO	J:155856
Cellular Component	GO:0042627	chylomicron	IBA	J:265628
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2425403
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6784616
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2425403
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IDA	J:40819
Cellular Component	GO:0005615	extracellular space	IDA	J:42632
Cellular Component	GO:0005615	extracellular space	IDA	J:22362
Cellular Component	GO:0034364	high-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0034364	high-density lipoprotein particle	IBA	J:265628
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0034361	very-low-density lipoprotein particle	ISO	J:164563
Biological Process	GO:0033344	cholesterol efflux	ISO	J:164563
Biological Process	GO:0033344	cholesterol efflux	IBA	J:265628
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IBA	J:265628
Biological Process	GO:0008203	cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	ISO	J:164563
Biological Process	GO:0042744	hydrogen peroxide catabolic process	ISO	J:164563
Biological Process	GO:0002227	innate immune response in mucosa	ISO	J:164563
Biological Process	GO:0002227	innate immune response in mucosa	IMP	J:91357
Biological Process	GO:0007159	leukocyte cell-cell adhesion	ISO	J:164563
Biological Process	GO:0016042	lipid catabolic process	ISO	J:164563
Biological Process	GO:0055088	lipid homeostasis	ISO	J:164563
Biological Process	GO:0006869	lipid transport	ISO	J:164563
Biological Process	GO:0042157	lipoprotein metabolic process	IEA	J:72247
Biological Process	GO:0034445	negative regulation of plasma lipoprotein oxidation	ISO	J:164563
Biological Process	GO:0046470	phosphatidylcholine metabolic process	ISO	J:164563
Biological Process	GO:0046470	phosphatidylcholine metabolic process	IBA	J:265628
Biological Process	GO:0033700	phospholipid efflux	ISO	J:164563
Biological Process	GO:0033700	phospholipid efflux	IBA	J:265628
Biological Process	GO:1905920	positive regulation of CoA-transferase activity	ISO	J:164563
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	ISO	J:164563
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	IBA	J:265628
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	IBA	J:265628
Biological Process	GO:0010898	positive regulation of triglyceride catabolic process	ISO	J:164563
Biological Process	GO:0010898	positive regulation of triglyceride catabolic process	IBA	J:265628
Biological Process	GO:0065005	protein-lipid complex assembly	ISO	J:164563
Biological Process	GO:0032374	regulation of cholesterol transport	ISO	J:164563
Biological Process	GO:0030300	regulation of intestinal cholesterol absorption	IBA	J:265628
Biological Process	GO:0030300	regulation of intestinal cholesterol absorption	IMP	J:43015
Biological Process	GO:0019430	removal of superoxide radicals	ISO	J:164563
Biological Process	GO:0006982	response to lipid hydroperoxide	ISO	J:164563
Biological Process	GO:0035634	response to stilbenoid	IEP	J:169896
Biological Process	GO:0043691	reverse cholesterol transport	ISO	J:164563
Biological Process	GO:0043691	reverse cholesterol transport	IBA	J:265628
Biological Process	GO:0070328	triglyceride homeostasis	IBA	J:265628
Biological Process	GO:0034372	very-low-density lipoprotein particle remodeling	ISO	J:164563
Biological Process	GO:0034372	very-low-density lipoprotein particle remodeling	IBA	J:265628