Apob GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Apob
apolipoprotein B
MGI:88052

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0120020	cholesterol transfer activity	ISO	J:164563
Molecular Function	GO:0120020	cholesterol transfer activity	IBA	J:265628
Molecular Function	GO:0008201	heparin binding	ISO	J:164563
Molecular Function	GO:0035473	lipase binding	ISO	J:164563
Molecular Function	GO:0005319	lipid transporter activity	IEA	J:72247
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	ISO	J:164563
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	IBA	J:265628
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Cellular Component	GO:0042627	chylomicron	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:78774
Cellular Component	GO:0070971	endoplasmic reticulum exit site	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2173779
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2173783
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2187263
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8933256
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8933295
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0034364	high-density lipoprotein particle	ISO	J:155856
Cellular Component	GO:0034363	intermediate-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005811	lipid droplet	IEA	J:60000
Cellular Component	GO:0034362	low-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0034362	low-density lipoprotein particle	ISO	J:155856
Cellular Component	GO:0034362	low-density lipoprotein particle	IBA	J:265628
Cellular Component	GO:0034359	mature chylomicron	ISO	J:164563
Cellular Component	GO:0034359	mature chylomicron	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:202649
Cellular Component	GO:0034361	very-low-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0034361	very-low-density lipoprotein particle	ISO	J:155856
Cellular Component	GO:0034361	very-low-density lipoprotein particle	IBA	J:265628
Cellular Component	GO:0031983	vesicle lumen	ISO	J:155856
Cellular Component	GO:0012506	vesicle membrane	ISO	J:155856
Biological Process	GO:0048844	artery morphogenesis	IGI	J:116827
Biological Process	GO:0033344	cholesterol efflux	IGI	J:185314
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IBA	J:265628
Biological Process	GO:0042632	cholesterol homeostasis	IGI	J:66424
Biological Process	GO:0042632	cholesterol homeostasis	IGI	J:66424
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:36426
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:23315
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:41510
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:46549
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:41510
Biological Process	GO:0042632	cholesterol homeostasis	IGI	J:116827
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:51549
Biological Process	GO:0008203	cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0030301	cholesterol transport	ISO	J:164563
Biological Process	GO:0030301	cholesterol transport	IBA	J:265628
Biological Process	GO:0030301	cholesterol transport	IMP	J:29700
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:87974
Biological Process	GO:0009566	fertilization	IMP	J:35836
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:35836
Biological Process	GO:0001701	in utero embryonic development	IMP	J:23315
Biological Process	GO:0001701	in utero embryonic development	IMP	J:46549
Biological Process	GO:0016042	lipid catabolic process	IMP	J:111086
Biological Process	GO:0006629	lipid metabolic process	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IDA	J:78774
Biological Process	GO:0006629	lipid metabolic process	IGI	J:66424
Biological Process	GO:0006629	lipid metabolic process	IGI	J:66424
Biological Process	GO:0006629	lipid metabolic process	IMP	J:16352
Biological Process	GO:0006629	lipid metabolic process	IMP	J:104784
Biological Process	GO:0006869	lipid transport	IEA	J:72247
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0042158	lipoprotein biosynthetic process	IGI	J:87974
Biological Process	GO:0042159	lipoprotein catabolic process	IGI	J:100500
Biological Process	GO:0042157	lipoprotein metabolic process	IGI	J:66424
Biological Process	GO:0042157	lipoprotein metabolic process	IGI	J:87974
Biological Process	GO:0042157	lipoprotein metabolic process	IMP	J:51549
Biological Process	GO:0042157	lipoprotein metabolic process	IMP	J:113171
Biological Process	GO:0042157	lipoprotein metabolic process	IMP	J:61175
Biological Process	GO:0042157	lipoprotein metabolic process	IMP	J:23315
Biological Process	GO:0042157	lipoprotein metabolic process	IGI	J:87974
Biological Process	GO:0042157	lipoprotein metabolic process	IGI	J:66424
Biological Process	GO:0042953	lipoprotein transport	IBA	J:265628
Biological Process	GO:0042953	lipoprotein transport	IGI	J:87974
Biological Process	GO:0042953	lipoprotein transport	IMP	J:87974
Biological Process	GO:0034383	low-density lipoprotein particle clearance	ISO	J:164563
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IMP	J:36426
Biological Process	GO:0007399	nervous system development	IMP	J:46549
Biological Process	GO:0007399	nervous system development	IMP	J:23315
Biological Process	GO:0010886	positive regulation of cholesterol storage	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:202649
Biological Process	GO:0010884	positive regulation of lipid storage	ISO	J:164563
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	ISO	J:164563
Biological Process	GO:0009791	post-embryonic development	IMP	J:51549
Biological Process	GO:0045540	regulation of cholesterol biosynthetic process	IMP	J:111086
Biological Process	GO:0009743	response to carbohydrate	ISO	J:155856
Biological Process	GO:0007283	spermatogenesis	IMP	J:35836
Biological Process	GO:0008202	steroid metabolic process	IEA	J:60000
Biological Process	GO:0019433	triglyceride catabolic process	ISO	J:155856
Biological Process	GO:0019433	triglyceride catabolic process	IMP	J:111086
Biological Process	GO:0006642	triglyceride mobilization	IBA	J:265628
Biological Process	GO:0006642	triglyceride mobilization	IMP	J:65191

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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