GO Annotations Graph

• Symbol: Apoc2
• Name: apolipoprotein C2
• ID: MGI:88054

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0055102	lipase inhibitor activity	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IBA	J:265628
Molecular Function	GO:0060230	lipoprotein lipase activator activity	ISO	J:164563
Molecular Function	GO:0060230	lipoprotein lipase activator activity	IBA	J:265628
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0016004	phospholipase activator activity	ISO	J:164563
Molecular Function	GO:0016004	phospholipase activator activity	IBA	J:265628
Molecular Function	GO:0043274	phospholipase binding	ISO	J:164563
Molecular Function	GO:0043274	phospholipase binding	IBA	J:265628
Cellular Component	GO:0042627	chylomicron	ISO	J:164563
Cellular Component	GO:0042627	chylomicron	IBA	J:265628
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2425403
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6784616
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2425403
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0034363	intermediate-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0034363	intermediate-density lipoprotein particle	IBA	J:265628
Cellular Component	GO:0034362	low-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0034362	low-density lipoprotein particle	IBA	J:265628
Cellular Component	GO:0034366	spherical high-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0034366	spherical high-density lipoprotein particle	IBA	J:265628
Cellular Component	GO:0034361	very-low-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0034361	very-low-density lipoprotein particle	IBA	J:265628
Biological Process	GO:0033344	cholesterol efflux	ISO	J:164563
Biological Process	GO:0034382	chylomicron remnant clearance	ISO	J:164563
Biological Process	GO:0034382	chylomicron remnant clearance	IBA	J:265628
Biological Process	GO:0034384	high-density lipoprotein particle clearance	ISO	J:164563
Biological Process	GO:0034384	high-density lipoprotein particle clearance	IBA	J:265628
Biological Process	GO:0042953	lipoprotein transport	ISO	J:155856
Biological Process	GO:0032375	negative regulation of cholesterol transport	ISO	J:164563
Biological Process	GO:0045833	negative regulation of lipid metabolic process	ISO	J:164563
Biological Process	GO:0048261	negative regulation of receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	ISO	J:164563
Biological Process	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	IBA	J:265628
Biological Process	GO:0033700	phospholipid efflux	ISO	J:164563
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	ISO	J:164563
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	IBA	J:265628
Biological Process	GO:0010518	positive regulation of phospholipase activity	ISO	J:164563
Biological Process	GO:0010518	positive regulation of phospholipase activity	IBA	J:265628
Biological Process	GO:0060697	positive regulation of phospholipid catabolic process	ISO	J:164563
Biological Process	GO:0060697	positive regulation of phospholipid catabolic process	IBA	J:265628
Biological Process	GO:0010898	positive regulation of triglyceride catabolic process	ISO	J:164563
Biological Process	GO:0070328	triglyceride homeostasis	ISO	J:164563