GO Annotations Graph

• Symbol: Ar
• Name: androgen receptor
• ID: MGI:88064

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005497	androgen binding	ISO	J:155856
Molecular Function	GO:0005497	androgen binding	ISO	J:164563
Molecular Function	GO:0051117	ATPase binding	ISO	J:122948
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:87326
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:105872
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:78409
Molecular Function	GO:0019899	enzyme binding	IPI	J:169894
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0034056	estrogen response element binding	IBA	J:265628
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:155856
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:155856
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:240274
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:207823
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:91599
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:78409
Molecular Function	GO:0070974	POU domain binding	IDA	J:153344
Molecular Function	GO:0005515	protein binding	IPI	J:200418
Molecular Function	GO:0005515	protein binding	IPI	J:153344
Molecular Function	GO:0005515	protein binding	IPI	J:100397
Molecular Function	GO:0005515	protein binding	IPI	J:252006
Molecular Function	GO:0005515	protein binding	IPI	J:244975
Molecular Function	GO:0005515	protein binding	IPI	J:153344
Molecular Function	GO:0005515	protein binding	IPI	J:105872
Molecular Function	GO:0005515	protein binding	IPI	J:138112
Molecular Function	GO:0005515	protein binding	IPI	J:87326
Molecular Function	GO:0005515	protein binding	IPI	J:99324
Molecular Function	GO:0005515	protein binding	IPI	J:171630
Molecular Function	GO:0005515	protein binding	IPI	J:78409
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0032553	ribonucleotide binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:17588
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005496	steroid binding	IEA	J:72247
Molecular Function	GO:0005496	steroid binding	IEA	J:60000
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:240274
Cellular Component	GO:0005737	cytoplasm	IDA	J:78409
Cellular Component	GO:0005737	cytoplasm	IDA	J:120960
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:240274
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:122327
Cellular Component	GO:0005634	nucleus	IDA	J:207823
Cellular Component	GO:0005634	nucleus	IDA	J:70204
Cellular Component	GO:0005634	nucleus	IDA	J:78409
Cellular Component	GO:0005634	nucleus	IDA	J:85611
Cellular Component	GO:0005634	nucleus	IPI	J:87326
Cellular Component	GO:0005634	nucleus	IDA	J:96238
Cellular Component	GO:0005634	nucleus	IDA	J:120960
Cellular Component	GO:0005634	nucleus	IDA	J:106511
Cellular Component	GO:0005634	nucleus	IDA	J:142809
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:138112
Cellular Component	GO:0032991	protein-containing complex	ISO	J:138112
Biological Process	GO:0060520	activation of prostate induction by androgen receptor signaling pathway	IMP	J:122327
Biological Process	GO:0030521	androgen receptor signaling pathway	ISO	J:155856
Biological Process	GO:0030521	androgen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030521	androgen receptor signaling pathway	IDA	J:240274
Biological Process	GO:0030521	androgen receptor signaling pathway	IDA	J:96238
Biological Process	GO:0030521	androgen receptor signaling pathway	IDA	J:91599
Biological Process	GO:0048645	animal organ formation	IMP	J:122327
Biological Process	GO:0048645	animal organ formation	IMP	J:122327
Biological Process	GO:0071391	cellular response to estrogen stimulus	ISO	J:164563
Biological Process	GO:0071383	cellular response to steroid hormone stimulus	ISO	J:164563
Biological Process	GO:0071394	cellular response to testosterone stimulus	IDA	J:240274
Biological Process	GO:0071394	cellular response to testosterone stimulus	ISO	J:164563
Biological Process	GO:0007620	copulation	ISO	J:155856
Biological Process	GO:0060742	epithelial cell differentiation involved in prostate gland development	IMP	J:123402
Biological Process	GO:0003382	epithelial cell morphogenesis	IGI	J:173897
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:123402
Biological Process	GO:0009566	fertilization	IMP	J:157337
Biological Process	GO:0001701	in utero embryonic development	IMP	J:83429
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	IMP	J:87193
Biological Process	GO:0030520	intracellular estrogen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030520	intracellular estrogen receptor signaling pathway	IMP	J:87193
Biological Process	GO:0030522	intracellular receptor signaling pathway	ISO	J:164563
Biological Process	GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	IMP	J:87193
Biological Process	GO:0033327	Leydig cell differentiation	IMP	J:157337
Biological Process	GO:0008049	male courtship behavior	ISO	J:155856
Biological Process	GO:0048808	male genitalia morphogenesis	IMP	J:148515
Biological Process	GO:0008584	male gonad development	IBA	J:265628
Biological Process	GO:0008584	male gonad development	IMP	J:83429
Biological Process	GO:0008584	male gonad development	IGI	J:173897
Biological Process	GO:0008584	male gonad development	IMP	J:157337
Biological Process	GO:0008584	male gonad development	IMP	J:122327
Biological Process	GO:0046661	male sex differentiation	ISO	J:155856
Biological Process	GO:0019102	male somatic sex determination	IMP	J:5173
Biological Process	GO:0060749	mammary gland alveolus development	IMP	J:87193
Biological Process	GO:0000165	MAPK cascade	IMP	J:87193
Biological Process	GO:0060571	morphogenesis of an epithelial fold	IMP	J:123402
Biological Process	GO:0035264	multicellular organism growth	IGI	J:157337
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:123402
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0045720	negative regulation of integrin biosynthetic process	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045597	positive regulation of cell differentiation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	IDA	J:71472
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	IMP	J:87193
Biological Process	GO:0045726	positive regulation of integrin biosynthetic process	ISO	J:164563
Biological Process	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	IMP	J:87193
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:87193
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0060406	positive regulation of penile erection	ISO	J:155856
Biological Process	GO:0042327	positive regulation of phosphorylation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:129602
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:105872
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:105872
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:210434
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:210434
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:171630
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:171630
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	ISO	J:164563
Biological Process	GO:0060740	prostate gland epithelium morphogenesis	IMP	J:123402
Biological Process	GO:0060736	prostate gland growth	IMP	J:122327
Biological Process	GO:0060736	prostate gland growth	IMP	J:123402
Biological Process	GO:0060736	prostate gland growth	IMP	J:122327
Biological Process	GO:0060736	prostate gland growth	IMP	J:122327
Biological Process	GO:0060736	prostate gland growth	IMP	J:123402
Biological Process	GO:0048638	regulation of developmental growth	IMP	J:122327
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:87326
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:78409
Biological Process	GO:0010468	regulation of gene expression	IMP	J:129602
Biological Process	GO:0010468	regulation of gene expression	IMP	J:224486
Biological Process	GO:0060685	regulation of prostatic bud formation	IGI	J:85295
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	IGI	J:138112
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:129602
Biological Process	GO:0019098	reproductive behavior	ISO	J:155856
Biological Process	GO:0048608	reproductive structure development	IMP	J:122327
Biological Process	GO:0048608	reproductive structure development	IMP	J:122327
Biological Process	GO:0061458	reproductive system development	IGI	J:157337
Biological Process	GO:0072520	seminiferous tubule development	IGI	J:173897
Biological Process	GO:0072520	seminiferous tubule development	IMP	J:157337
Biological Process	GO:0007338	single fertilization	IGI	J:173897
Biological Process	GO:0014734	skeletal muscle hypertrophy	ISO	J:155856
Biological Process	GO:0007283	spermatogenesis	ISO	J:155856
Biological Process	GO:0007283	spermatogenesis	IMP	J:137427
Biological Process	GO:0007283	spermatogenesis	IMP	J:157337
Biological Process	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis	IMP	J:87193
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:171630
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:210434
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:171630
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:210434