GO Annotations Graph

• Symbol: Arc
• Name: activity regulated cytoskeletal-associated protein
• ID: MGI:88067

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	TAS	J:61449
Molecular Function	GO:0003729	mRNA binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:249721
Molecular Function	GO:0005515	protein binding	IPI	J:194528
Molecular Function	GO:0005515	protein binding	IPI	J:186178
Molecular Function	GO:0005515	protein binding	IPI	J:178689
Molecular Function	GO:0005515	protein binding	IPI	J:152628
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	TAS	J:61449
Cellular Component	GO:0030425	dendrite	IDA	J:205779
Cellular Component	GO:0043197	dendritic spine	IDA	J:276388
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:1903561	extracellular vesicle	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:263451
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:263451
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263451
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263451
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	IDA	J:259121
Cellular Component	GO:0071598	neuronal ribonucleoprotein granule	IDA	J:205779
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098845	postsynaptic endosome	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IEA	J:60000
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:61449
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0007010	cytoskeleton organization	ISO	J:164563
Biological Process	GO:0007010	cytoskeleton organization	IBA	J:265628
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0007492	endoderm development	IMP	J:61449
Biological Process	GO:0007616	long-term memory	IMP	J:276388
Biological Process	GO:0007616	long-term memory	ISO	J:155856
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:276388
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0051028	mRNA transport	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	ISO	J:155856
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	IBA	J:265628
Biological Process	GO:0051260	protein homooligomerization	ISO	J:155856
Biological Process	GO:0022604	regulation of cell morphogenesis	ISO	J:164563
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	ISO	J:155856
Biological Process	GO:1900452	regulation of long-term synaptic depression	IDA	J:259121
Biological Process	GO:1900271	regulation of long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:1900271	regulation of long-term synaptic potentiation	IMP	J:276388
Biological Process	GO:1900271	regulation of long-term synaptic potentiation	IBA	J:265628
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	IBA	J:265628
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IMP	J:263451
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IDA	J:263451
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IMP	J:263451
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IDA	J:263451
Biological Process	GO:0110077	vesicle-mediated intercellular transport	ISO	J:155856