GO Annotations Graph

• Symbol: Arg1
• Name: arginase, liver
• ID: MGI:88070

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004053	arginase activity	ISO	J:155856
Molecular Function	GO:0004053	arginase activity	IBA	J:265628
Molecular Function	GO:0004053	arginase activity	IDA	J:46302
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	IEA	J:72247
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0030145	manganese ion binding	ISO	J:155856
Molecular Function	GO:0030145	manganese ion binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0019547	arginine catabolic process to ornithine	ISO	J:155856
Biological Process	GO:0019547	arginine catabolic process to ornithine	IBA	J:265628
Biological Process	GO:0006525	arginine metabolic process	ISO	J:155856
Biological Process	GO:0032964	collagen biosynthetic process	ISO	J:155856
Biological Process	GO:0042832	defense response to protozoan	IMP	J:243399
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0046007	negative regulation of activated T cell proliferation	IMP	J:243399
Biological Process	GO:0042130	negative regulation of T cell proliferation	ISO	J:164563
Biological Process	GO:2000552	negative regulation of T-helper 2 cell cytokine production	IMP	J:243399
Biological Process	GO:0060336	negative regulation of type II interferon-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0070965	positive regulation of neutrophil mediated killing of fungus	ISO	J:164563
Biological Process	GO:1905541	regulation of L-arginine import across plasma membrane	ISO	J:155856
Biological Process	GO:0000050	urea cycle	ISO	J:155856