GO Annotations Graph

• Symbol: Arsa
• Name: arylsulfatase A
• ID: MGI:88077

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004065	arylsulfatase activity	ISO	J:155856
Molecular Function	GO:0004065	arylsulfatase activity	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0004098	cerebroside-sulfatase activity	IEA	J:72245
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008484	sulfuric ester hydrolase activity	ISO	J:99578
Cellular Component	GO:0001669	acrosomal vesicle	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0031232	extrinsic component of external side of plasma membrane	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:77540
Cellular Component	GO:0005886	plasma membrane	IDA	J:77540
Biological Process	GO:0006914	autophagy	ISO	J:155856
Biological Process	GO:0007339	binding of sperm to zona pellucida	IMP	J:77540
Biological Process	GO:0007417	central nervous system development	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0043627	response to estrogen	ISO	J:155856
Biological Process	GO:0045471	response to ethanol	ISO	J:155856
Biological Process	GO:0051597	response to methylmercury	ISO	J:155856
Biological Process	GO:0007584	response to nutrient	ISO	J:155856
Biological Process	GO:0009268	response to pH	ISO	J:155856