GO Annotations Graph

• Symbol: Ass1
• Name: argininosuccinate synthetase 1
• ID: MGI:88090

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016597	amino acid binding	ISO	J:164563
Molecular Function	GO:0004055	argininosuccinate synthase activity	ISO	J:164563
Molecular Function	GO:0004055	argininosuccinate synthase activity	ISO	J:155856
Molecular Function	GO:0004055	argininosuccinate synthase activity	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:250437
Molecular Function	GO:0005515	protein binding	IPI	J:180208
Molecular Function	GO:0015643	toxic substance binding	ISO	J:155856
Cellular Component	GO:0070852	cell body fiber	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IDA	J:87578
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Biological Process	GO:0008652	amino acid biosynthetic process	IEA	J:60000
Biological Process	GO:0006526	arginine biosynthetic process	ISO	J:164563
Biological Process	GO:0006526	arginine biosynthetic process	ISO	J:155856
Biological Process	GO:0006526	arginine biosynthetic process	IBA	J:265628
Biological Process	GO:0000053	argininosuccinate metabolic process	ISO	J:164563
Biological Process	GO:0000053	argininosuccinate metabolic process	ISO	J:155856
Biological Process	GO:0000053	argininosuccinate metabolic process	IBA	J:265628
Biological Process	GO:0006531	aspartate metabolic process	ISO	J:164563
Biological Process	GO:0071499	cellular response to laminar fluid shear stress	ISO	J:164563
Biological Process	GO:0007623	circadian rhythm	ISO	J:164563
Biological Process	GO:0007623	circadian rhythm	IDA	J:250437
Biological Process	GO:0000052	citrulline metabolic process	ISO	J:164563
Biological Process	GO:1903038	negative regulation of leukocyte cell-cell adhesion	ISO	J:164563
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	ISO	J:164563
Biological Process	GO:0051384	response to glucocorticoid	ISO	J:155856
Biological Process	GO:0010046	response to mycotoxin	ISO	J:155856
Biological Process	GO:0010043	response to zinc ion	ISO	J:155856
Biological Process	GO:0000050	urea cycle	ISO	J:164563
Biological Process	GO:0000050	urea cycle	ISO	J:155856
Biological Process	GO:0000050	urea cycle	IBA	J:265628