GO Annotations Graph

• Symbol: Atp1a3
• Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide
• ID: MGI:88107

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:164563
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0031748	D1 dopamine receptor binding	ISO	J:155856
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	IPI	J:151007
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0008556	P-type potassium transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	ISO	J:164563
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	IBA	J:265628
Molecular Function	GO:0086037	P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential	IGI	J:151007
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:164563
Molecular Function	GO:0005215	transporter activity	IEA	J:72247
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:164563
Cellular Component	GO:0044305	calyx of Held	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:62912
Cellular Component	GO:0005737	cytoplasm	IDA	J:62912
Cellular Component	GO:0044327	dendritic spine head	ISO	J:155856
Cellular Component	GO:0044326	dendritic spine neck	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0098984	neuron to neuron synapse	IDA	J:168850
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:62912
Cellular Component	GO:0005634	nucleus	IDA	J:62912
Cellular Component	GO:0031090	organelle membrane	ISO	J:164563
Cellular Component	GO:0001917	photoreceptor inner segment	IDA	J:168850
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	IDA	J:151007
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ISO	J:155856
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	IDA	J:151007
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ISO	J:164563
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:117414
Biological Process	GO:0060048	cardiac muscle contraction	IDA	J:151007
Biological Process	GO:1904646	cellular response to amyloid-beta	ISO	J:155856
Biological Process	GO:0030007	intracellular potassium ion homeostasis	ISO	J:164563
Biological Process	GO:0030007	intracellular potassium ion homeostasis	IBA	J:265628
Biological Process	GO:0006883	intracellular sodium ion homeostasis	IDA	J:151007
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:164563
Biological Process	GO:0006883	intracellular sodium ion homeostasis	IBA	J:265628
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	IMP	J:117414
Biological Process	GO:0007613	memory	IMP	J:117414
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1990535	neuron projection maintenance	ISO	J:164563
Biological Process	GO:1990573	potassium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:1990573	potassium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	ISO	J:155856
Biological Process	GO:1902600	proton transmembrane transport	IBA	J:265628
Biological Process	GO:0086036	regulation of cardiac muscle cell membrane potential	IGI	J:151007
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:117414
Biological Process	GO:0036376	sodium ion export across plasma membrane	IDA	J:151007
Biological Process	GO:0036376	sodium ion export across plasma membrane	ISO	J:164563
Biological Process	GO:0036376	sodium ion export across plasma membrane	IBA	J:265628
Biological Process	GO:0006814	sodium ion transport	ISO	J:155856
Biological Process	GO:0008542	visual learning	IMP	J:117414