GO Annotations Graph

• Symbol: Atp1b1
• Name: ATPase, Na+/K+ transporting, beta 1 polypeptide
• ID: MGI:88108

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001671	ATPase activator activity	IMP	J:152596
Molecular Function	GO:0001671	ATPase activator activity	ISO	J:164563
Molecular Function	GO:0001671	ATPase activator activity	IBA	J:265628
Molecular Function	GO:0051117	ATPase binding	ISO	J:164563
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:100471
Molecular Function	GO:0005515	protein binding	IPI	J:184429
Molecular Function	GO:0005515	protein binding	IPI	J:125006
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	IPI	J:197851
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:176751
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:62912
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	IMP	J:152596
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0031090	organelle membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:62912
Cellular Component	GO:0005886	plasma membrane	IDA	J:62912
Cellular Component	GO:0042383	sarcolemma	IMP	J:152596
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	IMP	J:152596
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ISO	J:155856
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	ISO	J:164563
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	IBA	J:265628
Cellular Component	GO:0036126	sperm flagellum	ISO	J:164563
Cellular Component	GO:0030315	T-tubule	ISO	J:164563
Biological Process	GO:0046034	ATP metabolic process	ISO	J:164563
Biological Process	GO:0001824	blastocyst development	IMP	MGI:MGI:1888635
Biological Process	GO:0060048	cardiac muscle contraction	IMP	J:152596
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	NAS	J:319965
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:152596
Biological Process	GO:0030007	intracellular potassium ion homeostasis	ISO	J:164563
Biological Process	GO:0030007	intracellular potassium ion homeostasis	IBA	J:265628
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:164563
Biological Process	GO:0006883	intracellular sodium ion homeostasis	IBA	J:265628
Biological Process	GO:0086009	membrane repolarization	ISO	J:164563
Biological Process	GO:0030001	metal ion transport	ISO	J:155856
Biological Process	GO:0098655	monoatomic cation transmembrane transport	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	ISO	J:164563
Biological Process	GO:1903281	positive regulation of calcium:sodium antiporter activity	IMP	J:152596
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	ISO	J:164563
Biological Process	GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	IMP	J:152596
Biological Process	GO:1903288	positive regulation of potassium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:1901018	positive regulation of potassium ion transmembrane transporter activity	ISO	J:164563
Biological Process	GO:1903278	positive regulation of sodium ion export across plasma membrane	ISO	J:164563
Biological Process	GO:1990573	potassium ion import across plasma membrane	IMP	J:152596
Biological Process	GO:1990573	potassium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	ISO	J:155856
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	IMP	J:152596
Biological Process	GO:1902600	proton transmembrane transport	NAS	J:319965
Biological Process	GO:1903169	regulation of calcium ion transmembrane transport	IMP	J:152596
Biological Process	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	IMP	J:152596
Biological Process	GO:0010468	regulation of gene expression	IMP	J:152596
Biological Process	GO:0055119	relaxation of cardiac muscle	IMP	J:152596
Biological Process	GO:0001666	response to hypoxia	ISO	J:155856
Biological Process	GO:0036376	sodium ion export across plasma membrane	IMP	J:152596
Biological Process	GO:0036376	sodium ion export across plasma membrane	ISO	J:164563
Biological Process	GO:0036376	sodium ion export across plasma membrane	IBA	J:265628
Biological Process	GO:0035725	sodium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006814	sodium ion transport	ISO	J:155856