Bcr GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Bcr
BCR activator of RhoGEF and GTPase
MGI:88141

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	IDA	J:118168
Molecular Function	GO:0005096	GTPase activator activity	IGI	J:153997
Molecular Function	GO:0005096	GTPase activator activity	IDA	J:118168
Molecular Function	GO:0005096	GTPase activator activity	TAS	J:72425
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:216285
Molecular Function	GO:0005515	protein binding	IPI	J:118143
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:118168
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:165475
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:165475
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:118168
Cellular Component	GO:0014069	postsynaptic density	IDA	J:216285
Cellular Component	GO:0099092	postsynaptic density, intracellular component	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:194542
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:165475
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:165475
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0030036	actin cytoskeleton organization	IGI	J:118168
Biological Process	GO:0030036	actin cytoskeleton organization	IGI	J:118168
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:164563
Biological Process	GO:0007420	brain development	IGI	J:72425
Biological Process	GO:0016477	cell migration	IGI	J:118168
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:23804
Biological Process	GO:0060216	definitive hemopoiesis	IMP	J:23804
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:118168
Biological Process	GO:0048041	focal adhesion assembly	ISO	J:164563
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:23804
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:108010
Biological Process	GO:0065002	intracellular protein transmembrane transport	IMP	J:23804
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0030216	keratinocyte differentiation	ISO	J:164563
Biological Process	GO:1905517	macrophage migration	IGI	J:118168
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:165475
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:165475
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:165475
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:165475
Biological Process	GO:0060313	negative regulation of blood vessel remodeling	IMP	J:195022
Biological Process	GO:0002692	negative regulation of cellular extravasation	IMP	J:195022
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:153997
Biological Process	GO:1905522	negative regulation of macrophage migration	IGI	J:118168
Biological Process	GO:0043314	negative regulation of neutrophil degranulation	IGI	J:153997
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	IMP	J:23804
Biological Process	GO:0060268	negative regulation of respiratory burst	IMP	J:23804
Biological Process	GO:0050885	neuromuscular process controlling balance	IGI	J:108010
Biological Process	GO:0043312	neutrophil degranulation	IGI	J:153997
Biological Process	GO:0006909	phagocytosis	IGI	J:118168
Biological Process	GO:0006909	phagocytosis	IGI	J:118168
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	IEA	J:72247
Biological Process	GO:0050766	positive regulation of phagocytosis	IGI	J:118168
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:74002
Biological Process	GO:0051171	regulation of nitrogen compound metabolic process	IMP	J:23804
Biological Process	GO:0035023	regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0043114	regulation of vascular permeability	IMP	J:195022
Biological Process	GO:0003014	renal system process	IMP	J:23804
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:153997
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007264	small GTPase mediated signal transduction	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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