GO Annotations Graph

• Symbol: Bglap2
• Name: bone gamma-carboxyglutamate protein 2
• ID: MGI:88157

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0046848	hydroxyapatite binding	IBA	J:265628
Molecular Function	GO:0046848	hydroxyapatite binding	IDA	J:126780
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008147	structural constituent of bone	ISO	J:155856
Molecular Function	GO:0008147	structural constituent of bone	IBA	J:265628
Cellular Component	GO:0042995	cell projection	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IDA	J:126780
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Biological Process	GO:0031214	biomineral tissue development	IEA	J:60000
Biological Process	GO:0060348	bone development	IBA	J:265628
Biological Process	GO:0044242	cellular lipid catabolic process	IMP	J:126780
Biological Process	GO:0032869	cellular response to insulin stimulus	IGI	J:126780
Biological Process	GO:0032869	cellular response to insulin stimulus	IMP	J:126780
Biological Process	GO:0016311	dephosphorylation	ISO	J:155856
Biological Process	GO:0042593	glucose homeostasis	IMP	J:126780
Biological Process	GO:0001649	osteoblast differentiation	IBA	J:265628
Biological Process	GO:0031016	pancreas development	IMP	J:126780
Biological Process	GO:0032024	positive regulation of insulin secretion	IMP	J:126780
Biological Process	GO:0030500	regulation of bone mineralization	IEA	J:72247
Biological Process	GO:1900076	regulation of cellular response to insulin stimulus	IEA	J:72247
Biological Process	GO:0032571	response to vitamin K	IEA	J:72247
Biological Process	GO:0044342	type B pancreatic cell proliferation	IMP	J:126780