GO Annotations Graph

• Symbol: Bmp5
• Name: bone morphogenetic protein 5
• ID: MGI:88181

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070700	BMP receptor binding	IBA	J:265628
Molecular Function	GO:0070700	BMP receptor binding	ISO	J:22224
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0008083	growth factor activity	IEA	J:72247
Molecular Function	GO:0008083	growth factor activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:87049
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Biological Process	GO:1905069	allantois development	IGI	J:53294
Biological Process	GO:0097065	anterior head development	IMP	J:223062
Biological Process	GO:0048738	cardiac muscle tissue development	IGI	J:53294
Biological Process	GO:0060411	cardiac septum morphogenesis	IGI	J:53294
Biological Process	GO:0051216	cartilage development	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0060710	chorio-allantoic fusion	IGI	J:53294
Biological Process	GO:0043583	ear development	IMP	J:223062
Biological Process	GO:0043583	ear development	IMP	J:223062
Biological Process	GO:0043583	ear development	IMP	J:223062
Biological Process	GO:0003272	endocardial cushion formation	IGI	J:53294
Biological Process	GO:0061384	heart trabecula morphogenesis	IGI	J:53294
Biological Process	GO:0030902	hindbrain development	IGI	J:53294
Biological Process	GO:0030539	male genitalia development	IGI	J:48561
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0032348	negative regulation of aldosterone biosynthetic process	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:2000065	negative regulation of cortisol biosynthetic process	ISO	J:164563
Biological Process	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010894	negative regulation of steroid biosynthetic process	ISO	J:164563
Biological Process	GO:0021502	neural fold elevation formation	IGI	J:53294
Biological Process	GO:0001503	ossification	IEA	J:60000
Biological Process	GO:0007389	pattern specification process	IMP	J:3046
Biological Process	GO:0007389	pattern specification process	IMP	J:3046
Biological Process	GO:0007389	pattern specification process	IMP	J:3046
Biological Process	GO:0007389	pattern specification process	IMP	J:3046
Biological Process	GO:0003344	pericardium morphogenesis	IGI	J:53294
Biological Process	GO:0060037	pharyngeal system development	IGI	J:53294
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:1900006	positive regulation of dendrite development	ISO	J:164563
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:3046
Biological Process	GO:0001501	skeletal system development	IMP	J:3046
Biological Process	GO:0001501	skeletal system development	IMP	J:3046
Biological Process	GO:0001501	skeletal system development	IMP	J:3046
Biological Process	GO:0060395	SMAD protein signal transduction	IBA	J:265628
Biological Process	GO:0003323	type B pancreatic cell development	ISO	J:164563