GO Annotations Graph

• Symbol: Tspo
• Name: translocator protein
• ID: MGI:88222

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005497	androgen binding	ISO	J:155856
Molecular Function	GO:0008503	benzodiazepine receptor activity	ISO	J:155856
Molecular Function	GO:0015485	cholesterol binding	IBA	J:265628
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:224799
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:224799
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Biological Process	GO:0048266	behavioral response to pain	ISO	J:155856
Biological Process	GO:0006821	chloride transport	ISO	J:155856
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:155856
Biological Process	GO:0060242	contact inhibition	ISO	J:155856
Biological Process	GO:0072655	establishment of protein localization to mitochondrion	IMP	J:224799
Biological Process	GO:0008347	glial cell migration	ISO	J:155856
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0072656	maintenance of protein location in mitochondrion	IMP	J:224799
Biological Process	GO:0006811	monoatomic ion transport	ISO	J:155856
Biological Process	GO:1903579	negative regulation of ATP metabolic process	IMP	J:224799
Biological Process	GO:1903147	negative regulation of autophagy of mitochondrion	IMP	J:224799
Biological Process	GO:2000853	negative regulation of corticosterone secretion	ISO	J:155856
Biological Process	GO:0060253	negative regulation of glial cell proliferation	ISO	J:155856
Biological Process	GO:0010823	negative regulation of mitochondrion organization	IMP	J:224799
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	ISO	J:155856
Biological Process	GO:0031397	negative regulation of protein ubiquitination	IMP	J:224799
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0051928	positive regulation of calcium ion transport	ISO	J:155856
Biological Process	GO:0060252	positive regulation of glial cell proliferation	ISO	J:155856
Biological Process	GO:0051901	positive regulation of mitochondrial depolarization	ISO	J:155856
Biological Process	GO:0010940	positive regulation of necrotic cell death	ISO	J:155856
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	ISO	J:155856
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	IMP	J:224799
Biological Process	GO:0050810	regulation of steroid biosynthetic process	ISO	J:155856
Biological Process	GO:1905144	response to acetylcholine	ISO	J:155856
Biological Process	GO:0006694	steroid biosynthetic process	ISO	J:155856