GO Annotations Graph

• Symbol: Anxa6
• Name: annexin A6
• ID: MGI:88255

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0005262	calcium channel activity	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	ISO	J:164563
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	ISO	J:155856
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	IBA	J:265628
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:164563
Molecular Function	GO:0015485	cholesterol binding	ISO	J:164563
Molecular Function	GO:0015485	cholesterol binding	IBA	J:265628
Molecular Function	GO:0035374	chondroitin sulfate binding	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	ISO	J:164563
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	IBA	J:265628
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0001786	phosphatidylserine binding	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5332993
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0031902	late endosome membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:198595
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:91039
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Biological Process	GO:0097190	apoptotic signaling pathway	IMP	J:195700
Biological Process	GO:0097190	apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:0006816	calcium ion transport	IMP	J:75832
Biological Process	GO:0003418	growth plate cartilage chondrocyte differentiation	IBA	J:265628
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	IMP	J:195700
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	IBA	J:265628
Biological Process	GO:0034220	monoatomic ion transmembrane transport	ISO	J:164563
Biological Process	GO:0051283	negative regulation of sequestering of calcium ion	IBA	J:265628
Biological Process	GO:0001755	neural crest cell migration	IBA	J:265628
Biological Process	GO:0001778	plasma membrane repair	IBA	J:265628
Biological Process	GO:0006937	regulation of muscle contraction	IBA	J:265628
Biological Process	GO:0006937	regulation of muscle contraction	IMP	J:75832