GO Annotations Graph

• Symbol: Cbs
• Name: cystathionine beta-synthase
• ID: MGI:88285

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070025	carbon monoxide binding	ISO	J:164563
Molecular Function	GO:0004122	cystathionine beta-synthase activity	ISO	J:155856
Molecular Function	GO:0004122	cystathionine beta-synthase activity	ISO	J:164563
Molecular Function	GO:0004122	cystathionine beta-synthase activity	IBA	J:265628
Molecular Function	GO:0004122	cystathionine beta-synthase activity	IMP	J:23321
Molecular Function	GO:0004122	cystathionine beta-synthase activity	IMP	J:64041
Molecular Function	GO:0004124	cysteine synthase activity	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0020037	heme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0043167	ion binding	ISO	J:164563
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0072341	modified amino acid binding	ISO	J:164563
Molecular Function	GO:0070026	nitric oxide binding	ISO	J:164563
Molecular Function	GO:0050421	nitrite reductase (NO-forming) activity	ISO	J:164563
Molecular Function	GO:0019825	oxygen binding	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0030170	pyridoxal phosphate binding	ISO	J:164563
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0008652	amino acid biosynthetic process	IEA	J:60000
Biological Process	GO:0097746	blood vessel diameter maintenance	IMP	J:64041
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:109002
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	IMP	J:112538
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:155856
Biological Process	GO:0021587	cerebellum morphogenesis	IMP	J:102677
Biological Process	GO:0019344	cysteine biosynthetic process	ISO	J:164563
Biological Process	GO:0019344	cysteine biosynthetic process	IMP	J:90586
Biological Process	GO:0006535	cysteine biosynthetic process from serine	IBA	J:265628
Biological Process	GO:0019343	cysteine biosynthetic process via cystathionine	IEA	J:72247
Biological Process	GO:0042262	DNA protection	ISO	J:164563
Biological Process	GO:0001958	endochondral ossification	IMP	J:112538
Biological Process	GO:0001958	endochondral ossification	IMP	J:112538
Biological Process	GO:0043418	homocysteine catabolic process	ISO	J:164563
Biological Process	GO:0050667	homocysteine metabolic process	ISO	J:155856
Biological Process	GO:0050667	homocysteine metabolic process	ISO	J:164563
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:104247
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:112538
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:64885
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:89359
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:64041
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:23321
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:94045
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:112793
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:137226
Biological Process	GO:0050667	homocysteine metabolic process	IMP	J:112538
Biological Process	GO:0070814	hydrogen sulfide biosynthetic process	ISO	J:155856
Biological Process	GO:0070814	hydrogen sulfide biosynthetic process	ISO	J:164563
Biological Process	GO:0019448	L-cysteine catabolic process	ISO	J:164563
Biological Process	GO:0006565	L-serine catabolic process	ISO	J:164563
Biological Process	GO:0006563	L-serine metabolic process	ISO	J:164563
Biological Process	GO:0060135	maternal process involved in female pregnancy	IMP	J:114850
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043506	regulation of JUN kinase activity	IMP	J:90586
Biological Process	GO:0010749	regulation of nitric oxide mediated signal transduction	IMP	J:64041
Biological Process	GO:0051593	response to folic acid	IMP	J:64885
Biological Process	GO:0006801	superoxide metabolic process	IMP	J:64041
Biological Process	GO:0019346	transsulfuration	ISO	J:155856