Cacna1s GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cacna1s
calcium channel, voltage-dependent, L type, alpha 1S subunit
MGI:88294

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0036094	small molecule binding	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:103273
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IDA	J:87930
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0044327	dendritic spine head	ISO	J:155856
Cellular Component	GO:0031674	I band	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:37052
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:104730
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:87930
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:96149
Cellular Component	GO:0030315	T-tubule	ISO	J:164563
Cellular Component	GO:0030315	T-tubule	IDA	J:96149
Cellular Component	GO:0030315	T-tubule	IDA	J:37052
Cellular Component	GO:0030315	T-tubule	IDA	J:56913
Cellular Component	GO:0005891	voltage-gated calcium channel complex	ISO	J:155856
Cellular Component	GO:0005891	voltage-gated calcium channel complex	ISO	J:164563
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IBA	J:265628
Biological Process	GO:0098703	calcium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0070588	calcium ion transmembrane transport	NAS	J:320086
Biological Process	GO:0006816	calcium ion transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	IMP	J:641
Biological Process	GO:0006816	calcium ion transport	IMP	J:115325
Biological Process	GO:0006816	calcium ion transport	IDA	J:87930
Biological Process	GO:0006816	calcium ion transport	IMP	J:103273
Biological Process	GO:0007029	endoplasmic reticulum organization	IMP	J:5283
Biological Process	GO:0002074	extraocular skeletal muscle development	IMP	J:105090
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0055001	muscle cell development	IMP	J:5283
Biological Process	GO:0006936	muscle contraction	ISO	J:164563
Biological Process	GO:0006936	muscle contraction	IMP	J:15029
Biological Process	GO:0006936	muscle contraction	IDA	J:18533
Biological Process	GO:0006936	muscle contraction	IMP	J:7390
Biological Process	GO:0006936	muscle contraction	IMP	J:5371
Biological Process	GO:0007520	myoblast fusion	IMP	J:106306
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:7296
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:6592
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:7295
Biological Process	GO:0045933	positive regulation of muscle contraction	NAS	J:320086
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0043501	skeletal muscle adaptation	IMP	J:105758
Biological Process	GO:0048741	skeletal muscle fiber development	IMP	J:109963
Biological Process	GO:0048741	skeletal muscle fiber development	IMP	J:4724
Biological Process	GO:0048741	skeletal muscle fiber development	IDA	J:18533
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:14970
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:7644
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:28645
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:4466
Biological Process	GO:0001501	skeletal system development	IMP	J:7655
Biological Process	GO:0006941	striated muscle contraction	IMP	J:3462
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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