Cacna1b GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cacna1b
calcium channel, voltage-dependent, N type, alpha 1B subunit
MGI:88296

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IDA	J:207256
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005261	monoatomic cation channel activity	IEA	J:72247
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:169741
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:207256
Molecular Function	GO:0051721	protein phosphatase 2A binding	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:102559
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:89452
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:76458
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:92975
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:169741
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IDA	J:92975
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0048786	presynaptic active zone	IDA	J:222708
Cellular Component	GO:0048786	presynaptic active zone	IDA	J:222708
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IBA	J:265628
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IDA	J:57712
Biological Process	GO:0070509	calcium ion import	ISO	J:155856
Biological Process	GO:0098703	calcium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0070588	calcium ion transmembrane transport	IMP	J:102559
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	IMP	J:89452
Biological Process	GO:0006816	calcium ion transport	IMP	J:76458
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:102559
Biological Process	GO:0007626	locomotory behavior	IMP	J:84684
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0007269	neurotransmitter secretion	IMP	J:89452
Biological Process	GO:0001956	positive regulation of neurotransmitter secretion	ISO	J:155856
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:76458
Biological Process	GO:0051924	regulation of calcium ion transport	IMP	J:102559
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	ISO	J:155856
Biological Process	GO:0008016	regulation of heart contraction	IMP	J:76458
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:1904645	response to amyloid-beta	ISO	J:164563
Biological Process	GO:0014070	response to organic cyclic compound	ISO	J:155856
Biological Process	GO:0048265	response to pain	IMP	J:102559
Biological Process	GO:0033574	response to testosterone	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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