Ccnd1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ccnd1
cyclin D1
MGI:88313

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	ISO	J:164563
Molecular Function	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IBA	J:265628
Molecular Function	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IDA	J:81172
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IDA	J:78410
Molecular Function	GO:0070064	proline-rich region binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:105043
Molecular Function	GO:0005515	protein binding	IPI	J:105045
Molecular Function	GO:0005515	protein binding	IPI	J:28743
Molecular Function	GO:0005515	protein binding	IPI	J:165553
Molecular Function	GO:0005515	protein binding	IPI	J:165553
Molecular Function	GO:0005515	protein binding	IPI	J:158603
Molecular Function	GO:0005515	protein binding	IPI	J:125912
Molecular Function	GO:0005515	protein binding	IPI	J:127604
Molecular Function	GO:0005515	protein binding	IPI	J:111799
Molecular Function	GO:0005515	protein binding	IPI	J:162977
Molecular Function	GO:0005515	protein binding	IPI	J:201309
Molecular Function	GO:0005515	protein binding	IPI	J:182377
Molecular Function	GO:0005515	protein binding	IPI	J:82317
Molecular Function	GO:0005515	protein binding	IPI	J:182969
Molecular Function	GO:0005515	protein binding	IPI	J:77848
Molecular Function	GO:0005515	protein binding	IPI	J:218799
Molecular Function	GO:0005515	protein binding	IPI	J:82317
Molecular Function	GO:0004672	protein kinase activity	IDA	J:82317
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	IPI	J:162977
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:182969
Cellular Component	GO:0097128	cyclin D1-CDK4 complex	IPI	J:127604
Cellular Component	GO:0097128	cyclin D1-CDK4 complex	ISO	J:164563
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	IPI	J:162977
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	ISO	J:164563
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	IBA	J:265628
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	IPI	J:85809
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:178645
Cellular Component	GO:0005737	cytoplasm	IDA	J:230033
Cellular Component	GO:0005737	cytoplasm	IDA	J:150130
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-182564
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-182564
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4395232
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:162977
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:92787
Cellular Component	GO:0005634	nucleus	IDA	J:92787
Cellular Component	GO:0005634	nucleus	IDA	J:92787
Cellular Component	GO:0005634	nucleus	IDA	J:106653
Cellular Component	GO:0005634	nucleus	IDA	J:178645
Cellular Component	GO:0005634	nucleus	IDA	J:37447
Cellular Component	GO:0005634	nucleus	IDA	J:81172
Cellular Component	GO:0005634	nucleus	IDA	J:218237
Cellular Component	GO:0005634	nucleus	IDA	J:230033
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0008283	cell population proliferation	IMP	J:301859
Biological Process	GO:0071310	cellular response to organic substance	IDA	J:145651
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IDA	J:107108
Biological Process	GO:0045444	fat cell differentiation	IDA	J:81172
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	NAS	J:320000
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	IDA	J:107108
Biological Process	GO:0007595	lactation	IGI	J:90978
Biological Process	GO:0007595	lactation	IMP	J:56642
Biological Process	GO:0033327	Leydig cell differentiation	ISO	J:155856
Biological Process	GO:0097421	liver regeneration	IDA	J:201786
Biological Process	GO:0060749	mammary gland alveolus development	IGI	J:90978
Biological Process	GO:0060749	mammary gland alveolus development	IMP	J:56642
Biological Process	GO:0033598	mammary gland epithelial cell proliferation	IGI	J:158376
Biological Process	GO:0033598	mammary gland epithelial cell proliferation	IGI	J:158376
Biological Process	GO:0033598	mammary gland epithelial cell proliferation	IGI	J:90978
Biological Process	GO:0044772	mitotic cell cycle phase transition	IBA	J:265628
Biological Process	GO:0031571	mitotic G1 DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IGI	J:92787
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:301859
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:92787
Biological Process	GO:0030182	neuron differentiation	IMP	J:301859
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0033601	positive regulation of mammary gland epithelial cell proliferation	IGI	J:158376
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:78410
Biological Process	GO:0006468	protein phosphorylation	IDA	J:82317
Biological Process	GO:0000320	re-entry into mitotic cell cycle	IDA	J:81172
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:74002
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:82317
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IBA	J:265628
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	IGI	J:182969
Biological Process	GO:0044321	response to leptin	ISO	J:164563
Biological Process	GO:0010243	response to organonitrogen compound	ISO	J:155856
Biological Process	GO:0070141	response to UV-A	ISO	J:164563
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:142037

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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