GO Annotations Graph

• Symbol: Cd14
• Name: CD14 antigen
• ID: MGI:88318

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001530	lipopolysaccharide binding	IBA	J:265628
Molecular Function	GO:0001530	lipopolysaccharide binding	ISO	J:73065
Molecular Function	GO:0001875	lipopolysaccharide immune receptor activity	ISO	J:164563
Molecular Function	GO:0070891	lipoteichoic acid binding	ISO	J:73065
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:32729
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:147119
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0046696	lipopolysaccharide receptor complex	ISO	J:164563
Cellular Component	GO:0046696	lipopolysaccharide receptor complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	IDA	J:125623
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0002752	cell surface pattern recognition receptor signaling pathway	ISO	J:164563
Biological Process	GO:0071726	cellular response to diacyl bacterial lipopeptide	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:32729
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:222669
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:73065
Biological Process	GO:0071223	cellular response to lipoteichoic acid	ISO	J:73065
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	ISO	J:164563
Biological Process	GO:0071727	cellular response to triacyl bacterial lipopeptide	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	ISO	J:155856
Biological Process	GO:0006954	inflammatory response	IBA	J:265628
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0001819	positive regulation of cytokine production	ISO	J:155856
Biological Process	GO:0045807	positive regulation of endocytosis	IMP	J:178826
Biological Process	GO:0032757	positive regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	IMP	J:222669
Biological Process	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	IMP	J:222669
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:32729
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:73065
Biological Process	GO:0032481	positive regulation of type I interferon production	IMP	J:178826
Biological Process	GO:0032481	positive regulation of type I interferon production	IBA	J:265628
Biological Process	GO:0032729	positive regulation of type II interferon production	IMP	J:222669
Biological Process	GO:0032729	positive regulation of type II interferon production	IBA	J:265628
Biological Process	GO:0006898	receptor-mediated endocytosis	IMP	J:178826
Biological Process	GO:0009617	response to bacterium	IMP	J:32729
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0002237	response to molecule of bacterial origin	IDA	J:125623
Biological Process	GO:0034612	response to tumor necrosis factor	ISO	J:155856
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	ISO	J:164563