GO Annotations Graph

• Symbol: Cd22
• Name: CD22 antigen
• ID: MGI:88322

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030246	carbohydrate binding	IEA	J:60000
Molecular Function	GO:0042609	CD4 receptor binding	IPI	J:265798
Molecular Function	GO:0042609	CD4 receptor binding	IBA	J:265628
Molecular Function	GO:0015026	coreceptor activity	TAS	J:72278
Molecular Function	GO:0005515	protein binding	IPI	J:72778
Molecular Function	GO:0005515	protein binding	IPI	J:200343
Molecular Function	GO:0005515	protein binding	IPI	J:116377
Molecular Function	GO:0019903	protein phosphatase binding	IPI	J:265798
Molecular Function	GO:0019903	protein phosphatase binding	IBA	J:265628
Molecular Function	GO:0033691	sialic acid binding	IPI	J:265798
Molecular Function	GO:0033691	sialic acid binding	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:265625
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005769	early endosome	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:64281
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0032809	neuronal cell body membrane	IDA	J:265625
Cellular Component	GO:0005886	plasma membrane	IPI	J:72278
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0055037	recycling endosome	IBA	J:265628
Biological Process	GO:0042113	B cell activation	ISO	J:164563
Biological Process	GO:0042113	B cell activation	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007166	cell surface receptor signaling pathway	TAS	J:72278
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	IBA	J:265628
Biological Process	GO:0050849	negative regulation of calcium-mediated signaling	IGI	J:160078
Biological Process	GO:0002638	negative regulation of immunoglobulin production	IGI	J:160078
Biological Process	GO:0030888	regulation of B cell proliferation	IGI	J:160078
Biological Process	GO:0030888	regulation of B cell proliferation	IBA	J:265628
Biological Process	GO:0030100	regulation of endocytosis	ISO	J:164563
Biological Process	GO:0050776	regulation of immune response	IGI	J:160078