GO Annotations Graph

• Symbol: Cd44
• Name: CD44 antigen
• ID: MGI:88338

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0038024	cargo receptor activity	IMP	J:323609
Molecular Function	GO:0038024	cargo receptor activity	IDA	J:323609
Molecular Function	GO:0038024	cargo receptor activity	IDA	J:323607
Molecular Function	GO:0038024	cargo receptor activity	ISO	J:323606
Molecular Function	GO:0016247	channel regulator activity	ISO	J:323605
Molecular Function	GO:0019955	cytokine binding	IDA	J:131317
Molecular Function	GO:0004896	cytokine receptor activity	ISO	J:164563
Molecular Function	GO:0004896	cytokine receptor activity	IDA	J:114878
Molecular Function	GO:0004896	cytokine receptor activity	IBA	J:265628
Molecular Function	GO:0005154	epidermal growth factor receptor binding	ISO	J:155856
Molecular Function	GO:0005540	hyaluronic acid binding	ISO	J:164563
Molecular Function	GO:0005540	hyaluronic acid binding	IBA	J:265628
Molecular Function	GO:0005540	hyaluronic acid binding	IMP	J:81768
Molecular Function	GO:0051219	phosphoprotein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:131317
Molecular Function	GO:0005515	protein binding	IPI	J:224716
Molecular Function	GO:0005515	protein binding	IPI	J:122713
Molecular Function	GO:0005515	protein binding	IPI	J:224716
Molecular Function	GO:0005515	protein binding	IPI	J:255604
Molecular Function	GO:0005515	protein binding	IPI	J:156410
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IBA	J:265628
Molecular Function	GO:0005114	type II transforming growth factor beta receptor binding	IPI	J:224716
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:52818
Cellular Component	GO:0042995	cell projection	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:224716
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:126749
Cellular Component	GO:0009986	cell surface	IDA	J:43157
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:147119
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:113553
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:25159
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:93953
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:144049
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:118845
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:63425
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:39748
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:177992
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:141392
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:93953
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:152384
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:53400
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:113553
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:174203
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:118947
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:88001
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:35057
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:64279
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:96628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:174697
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:86758
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:60915
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:98417
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:92679
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:155686
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:140498
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:89320
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:163754
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:172134
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:102496
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:19636
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0031258	lamellipodium membrane	ISO	J:164563
Cellular Component	GO:0035692	macrophage migration inhibitory factor receptor complex	ISO	J:164563
Cellular Component	GO:0035692	macrophage migration inhibitory factor receptor complex	IDA	J:131317
Cellular Component	GO:0035692	macrophage migration inhibitory factor receptor complex	IDA	J:114878
Cellular Component	GO:0035692	macrophage migration inhibitory factor receptor complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	ISO	J:323605
Cellular Component	GO:0045121	membrane raft	ISO	J:323606
Cellular Component	GO:0005902	microvillus	IDA	J:255604
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:43768
Cellular Component	GO:0005886	plasma membrane	IDA	J:130833
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0060442	branching involved in prostate gland morphogenesis	IMP	J:43768
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IMP	J:81768
Biological Process	GO:0007155	cell adhesion	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	ISO	J:155856
Biological Process	GO:0007155	cell adhesion	IBA	J:265628
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0016477	cell migration	ISO	J:155856
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	ISO	J:164563
Biological Process	GO:0030214	hyaluronan catabolic process	ISO	J:164563
Biological Process	GO:0030214	hyaluronan catabolic process	ISO	J:323606
Biological Process	GO:0030214	hyaluronan catabolic process	IDA	J:323609
Biological Process	GO:0030214	hyaluronan catabolic process	ISO	J:323605
Biological Process	GO:0030214	hyaluronan catabolic process	IMP	J:323609
Biological Process	GO:0006954	inflammatory response	IBA	J:265628
Biological Process	GO:0034238	macrophage fusion	ISO	J:155856
Biological Process	GO:0070487	monocyte aggregation	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	IMP	J:224716
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	IMP	J:114878
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:224716
Biological Process	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	ISO	J:164563
Biological Process	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:114878
Biological Process	GO:0002906	negative regulation of mature B cell apoptotic process	IDA	J:131317
Biological Process	GO:0045590	negative regulation of regulatory T cell differentiation	IMP	J:224716
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0002821	positive regulation of adaptive immune response	NAS	J:131317
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:114878
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IBA	J:265628
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:224716
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:51126
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:51126
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	ISO	J:164563
Biological Process	GO:1900625	positive regulation of monocyte aggregation	ISO	J:164563
Biological Process	GO:0033031	positive regulation of neutrophil apoptotic process	ISO	J:155856
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IMP	J:114878
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IMP	J:114878
Biological Process	GO:0006898	receptor-mediated endocytosis	IMP	J:323609
Biological Process	GO:0006898	receptor-mediated endocytosis	IDA	J:323609
Biological Process	GO:0001558	regulation of cell growth	ISO	J:155856
Biological Process	GO:2000392	regulation of lamellipodium morphogenesis	ISO	J:164563
Biological Process	GO:0042110	T cell activation	ISO	J:164563
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:142037
Biological Process	GO:0002246	wound healing involved in inflammatory response	IMP	J:111216
Biological Process	GO:0044319	wound healing, spreading of cells	ISO	J:164563