Cd8a GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cd8a
CD8 subunit alpha
MGI:88346

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	IPI	J:97692
Molecular Function	GO:0023024	MHC class I protein complex binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:115170
Molecular Function	GO:0005515	protein binding	IPI	J:204615
Molecular Function	GO:0005515	protein binding	IPI	J:97692
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:86195
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:155686
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:140498
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:141145
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:53400
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:177992
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:63425
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:98417
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:92721
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:120804
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:141431
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:174697
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:60915
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:149909
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:41170
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:132871
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:92721
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:7488
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:96628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:91939
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:103896
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:59927
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:152384
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:31364
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:39981
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:143981
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:68956
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:92679
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:146983
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:113553
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:163829
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:86758
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:145327
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:157744
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:172134
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:31364
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:127083
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:97996
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:34311
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0044853	plasma membrane raft	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	IPI	J:314080
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Biological Process	GO:0002250	adaptive immune response	NAS	J:314080
Biological Process	GO:0019722	calcium-mediated signaling	IDA	J:41170
Biological Process	GO:0007166	cell surface receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007166	cell surface receptor signaling pathway	IDA	J:41170
Biological Process	GO:0045065	cytotoxic T cell differentiation	IBA	J:265628
Biological Process	GO:0045065	cytotoxic T cell differentiation	IMP	J:68956
Biological Process	GO:0051607	defense response to virus	IDA	J:143981
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	IDA	J:41170
Biological Process	GO:0042110	T cell activation	ISO	J:164563
Biological Process	GO:0042110	T cell activation	ISO	J:155856
Biological Process	GO:0002456	T cell mediated immunity	IBA	J:265628
Biological Process	GO:0002456	T cell mediated immunity	IMP	J:68956
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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