GO Annotations Graph

• Symbol: Cdh1
• Name: cadherin 1
• ID: MGI:88354

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045294	alpha-catenin binding	IPI	J:35077
Molecular Function	GO:0030506	ankyrin binding	ISO	J:164563
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0008013	beta-catenin binding	IPI	J:240307
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:155856
Molecular Function	GO:0008013	beta-catenin binding	IDA	J:22125
Molecular Function	GO:0008013	beta-catenin binding	IPI	J:88895
Molecular Function	GO:0008013	beta-catenin binding	IPI	J:35077
Molecular Function	GO:0008013	beta-catenin binding	IPI	J:92091
Molecular Function	GO:0045296	cadherin binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IDA	J:80763
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:164563
Molecular Function	GO:0008092	cytoskeletal protein binding	IMP	J:1648
Molecular Function	GO:0045295	gamma-catenin binding	ISO	J:164563
Molecular Function	GO:0032794	GTPase activating protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:245244
Molecular Function	GO:0042802	identical protein binding	IPI	J:245287
Molecular Function	GO:0042802	identical protein binding	IPI	J:245281
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:245329
Molecular Function	GO:0042802	identical protein binding	IPI	J:80763
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0060090	molecular adaptor activity	IDA	J:240307
Molecular Function	GO:0060090	molecular adaptor activity	EXP	J:240307
Molecular Function	GO:0005515	protein binding	IPI	J:116387
Molecular Function	GO:0005515	protein binding	IPI	J:326898
Molecular Function	GO:0005515	protein binding	IPI	J:200349
Molecular Function	GO:0005515	protein binding	IPI	J:273548
Molecular Function	GO:0005515	protein binding	IPI	J:187624
Molecular Function	GO:0005515	protein binding	IPI	J:220301
Molecular Function	GO:0005515	protein binding	IPI	J:164742
Molecular Function	GO:0005515	protein binding	IPI	J:174365
Molecular Function	GO:0005515	protein binding	IPI	J:127227
Molecular Function	GO:0005515	protein binding	IPI	J:201251
Molecular Function	GO:0005515	protein binding	IPI	J:182415
Molecular Function	GO:0005515	protein binding	IPI	J:245255
Molecular Function	GO:0005515	protein binding	IPI	J:85670
Molecular Function	GO:0005515	protein binding	IPI	J:83415
Molecular Function	GO:0005515	protein binding	IPI	J:115561
Molecular Function	GO:0005515	protein binding	IPI	J:82758
Molecular Function	GO:0005515	protein binding	IPI	J:114547
Molecular Function	GO:0005515	protein binding	IPI	J:91529
Molecular Function	GO:0005515	protein binding	IPI	J:105729
Molecular Function	GO:0005515	protein binding	IPI	J:235660
Molecular Function	GO:0005515	protein binding	IPI	J:66255
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:142596
Molecular Function	GO:0019903	protein phosphatase binding	IPI	J:114547
Molecular Function	GO:1990782	protein tyrosine kinase binding	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IDA	J:236209
Cellular Component	GO:0005912	adherens junction	IDA	J:276414
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:94940
Cellular Component	GO:0005912	adherens junction	IDA	J:97750
Cellular Component	GO:0005912	adherens junction	IDA	J:198627
Cellular Component	GO:0005912	adherens junction	IDA	J:83082
Cellular Component	GO:0005912	adherens junction	IDA	J:29881
Cellular Component	GO:0005912	adherens junction	IDA	J:98502
Cellular Component	GO:0005912	adherens junction	IDA	J:198627
Cellular Component	GO:0005912	adherens junction	IDA	J:124808
Cellular Component	GO:0005912	adherens junction	IDA	J:72801
Cellular Component	GO:0005912	adherens junction	IDA	J:182970
Cellular Component	GO:0005912	adherens junction	IDA	J:124995
Cellular Component	GO:0005912	adherens junction	ISO	J:300338
Cellular Component	GO:0043296	apical junction complex	ISO	J:164563
Cellular Component	GO:0043296	apical junction complex	IDA	J:117344
Cellular Component	GO:0043296	apical junction complex	IDA	J:206363
Cellular Component	GO:0045177	apical part of cell	IDA	J:88495
Cellular Component	GO:0030424	axon	IDA	J:120130
Cellular Component	GO:0043679	axon terminus	IDA	J:120130
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:98502
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:157099
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:202984
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:194289
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:161201
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:159723
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:165751
Cellular Component	GO:0016342	catenin complex	ISO	J:164563
Cellular Component	GO:0016342	catenin complex	IMP	J:240307
Cellular Component	GO:0016342	catenin complex	IBA	J:265628
Cellular Component	GO:0016342	catenin complex	IDA	J:35077
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0071944	cell periphery	IDA	J:148987
Cellular Component	GO:0071944	cell periphery	IDA	J:226938
Cellular Component	GO:0009986	cell surface	IDA	J:71108
Cellular Component	GO:0005911	cell-cell junction	IDA	J:204548
Cellular Component	GO:0005911	cell-cell junction	IDA	J:297286
Cellular Component	GO:0005911	cell-cell junction	IDA	J:136803
Cellular Component	GO:0005911	cell-cell junction	IDA	J:53123
Cellular Component	GO:0005911	cell-cell junction	IDA	J:169829
Cellular Component	GO:0005911	cell-cell junction	IDA	J:136803
Cellular Component	GO:0005911	cell-cell junction	IDA	J:203796
Cellular Component	GO:0005911	cell-cell junction	IDA	J:71108
Cellular Component	GO:0005911	cell-cell junction	IDA	J:136803
Cellular Component	GO:0005911	cell-cell junction	IDA	J:163736
Cellular Component	GO:0005911	cell-cell junction	IDA	J:171374
Cellular Component	GO:0005911	cell-cell junction	IDA	J:51903
Cellular Component	GO:0005911	cell-cell junction	IDA	J:159723
Cellular Component	GO:0005911	cell-cell junction	IDA	J:143362
Cellular Component	GO:0005911	cell-cell junction	IDA	J:90107
Cellular Component	GO:0005911	cell-cell junction	ISO	J:73065
Cellular Component	GO:0005911	cell-cell junction	ISO	J:73065
Cellular Component	GO:0005911	cell-cell junction	IDA	J:136803
Cellular Component	GO:0005911	cell-cell junction	IDA	J:117056
Cellular Component	GO:0005911	cell-cell junction	ISO	J:188708
Cellular Component	GO:0005911	cell-cell junction	IDA	J:145651
Cellular Component	GO:0005911	cell-cell junction	IDA	J:179634
Cellular Component	GO:0005911	cell-cell junction	IDA	J:158532
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:198562
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0016600	flotillin complex	ISO	J:164563
Cellular Component	GO:0016600	flotillin complex	IDA	J:220503
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0043219	lateral loop	IDA	J:159103
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005902	microvillus	IDA	J:300338
Cellular Component	GO:0033268	node of Ranvier	IDA	J:159103
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:296096
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-199089
Cellular Component	GO:0005886	plasma membrane	IDA	J:151537
Cellular Component	GO:0005886	plasma membrane	IDA	J:142136
Cellular Component	GO:0005886	plasma membrane	IDA	J:158680
Cellular Component	GO:0005886	plasma membrane	IDA	J:103553
Cellular Component	GO:0005886	plasma membrane	IDA	J:77502
Cellular Component	GO:0005886	plasma membrane	IDA	J:105239
Cellular Component	GO:0005886	plasma membrane	IDA	J:128085
Cellular Component	GO:0005886	plasma membrane	IDA	J:67042
Cellular Component	GO:0005886	plasma membrane	IDA	J:101038
Cellular Component	GO:0005886	plasma membrane	IDA	J:35077
Cellular Component	GO:0005886	plasma membrane	IDA	J:306470
Cellular Component	GO:0005886	plasma membrane	IDA	J:97065
Cellular Component	GO:0005886	plasma membrane	IDA	J:88895
Cellular Component	GO:0005886	plasma membrane	IDA	J:105284
Cellular Component	GO:0005886	plasma membrane	IDA	J:132812
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	IDA	J:159103
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:128085
Biological Process	GO:0034332	adherens junction organization	ISO	J:164563
Biological Process	GO:0034332	adherens junction organization	IBA	J:265628
Biological Process	GO:0070830	bicellular tight junction assembly	IMP	J:97223
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IBA	J:265628
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IDA	J:88895
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:190582
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:190582
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0000902	cell morphogenesis	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:164563
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:105729
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:91137
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	IBA	J:265628
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	IMP	J:128085
Biological Process	GO:0007043	cell-cell junction assembly	IBA	J:265628
Biological Process	GO:0071230	cellular response to amino acid stimulus	IDA	J:164409
Biological Process	GO:0071681	cellular response to indole-3-methanol	ISO	J:164563
Biological Process	GO:0071285	cellular response to lithium ion	ISO	J:164563
Biological Process	GO:0090102	cochlea development	IDA	J:276414
Biological Process	GO:0090102	cochlea development	IMP	J:178162
Biological Process	GO:0046697	decidualization	IMP	J:185830
Biological Process	GO:0007566	embryo implantation	IMP	J:185830
Biological Process	GO:0003382	epithelial cell morphogenesis	IMP	J:190582
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:97223
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IEA	J:72247
Biological Process	GO:0001701	in utero embryonic development	IMP	J:97223
Biological Process	GO:0060576	intestinal epithelial cell development	IMP	J:190582
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0030517	negative regulation of axon extension	ISO	J:155856
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IMP	J:190582
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	ISO	J:164563
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:190582
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	IMP	J:128085
Biological Process	GO:0010955	negative regulation of protein processing	IMP	J:127491
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	IMP	J:1648
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0042307	positive regulation of protein import into nucleus	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IDA	J:220503
Biological Process	GO:0072659	protein localization to plasma membrane	IDA	J:22125
Biological Process	GO:0019538	protein metabolic process	IDA	J:82758
Biological Process	GO:0060693	regulation of branching involved in salivary gland morphogenesis	IMP	J:143362
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:91529
Biological Process	GO:0010468	regulation of gene expression	ISO	J:164563
Biological Process	GO:2001222	regulation of neuron migration	IDA	J:197573
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	ISO	J:155856
Biological Process	GO:0032880	regulation of protein localization	IMP	J:97223
Biological Process	GO:2000008	regulation of protein localization to cell surface	IMP	J:97223
Biological Process	GO:0060662	salivary gland cavitation	IMP	J:143362
Biological Process	GO:0007605	sensory perception of sound	IMP	J:178162
Biological Process	GO:0007416	synapse assembly	ISO	J:155856
Biological Process	GO:0007416	synapse assembly	IBA	J:265628
Biological Process	GO:0001829	trophectodermal cell differentiation	IMP	J:117056
Biological Process	GO:0035847	uterine epithelium development	IMP	J:185830