GO Annotations Graph

• Symbol: Cenpa
• Name: centromere protein A
• ID: MGI:88375

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0046982	protein heterodimerization activity	IEA	J:72247
Molecular Function	GO:0030527	structural constituent of chromatin	IEA	J:72247
Cellular Component	GO:0061638	CENP-A containing chromatin	IDA	J:86777
Cellular Component	GO:0043505	CENP-A containing nucleosome	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	ISO	J:164563
Cellular Component	GO:0000775	chromosome, centromeric region	ISO	J:86384
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:188023
Cellular Component	GO:0000779	condensed chromosome, centromeric region	ISO	J:164563
Cellular Component	GO:0000779	condensed chromosome, centromeric region	IDA	J:92329
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0000786	nucleosome	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005721	pericentric heterochromatin	IDA	J:92329
Biological Process	GO:0034080	CENP-A containing chromatin assembly	ISO	J:164563
Biological Process	GO:0000132	establishment of mitotic spindle orientation	ISO	J:164563
Biological Process	GO:0051382	kinetochore assembly	ISO	J:164563
Biological Process	GO:0000281	mitotic cytokinesis	ISO	J:164563
Biological Process	GO:0061644	protein localization to CENP-A containing chromatin	NAS	J:320333
Biological Process	GO:0071459	protein localization to chromosome, centromeric region	ISO	J:164563