Cfh GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cfh
complement component factor h
MGI:88385

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001851	complement component C3b binding	IBA	J:265628
Molecular Function	GO:0001851	complement component C3b binding	IPI	J:116059
Molecular Function	GO:0001851	complement component C3b binding	IPI	J:105012
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	ISO	J:164563
Molecular Function	GO:0008201	heparin binding	ISO	J:164563
Molecular Function	GO:0008201	heparin binding	IDA	J:116059
Molecular Function	GO:0008201	heparin binding	IDA	J:105012
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:242465
Molecular Function	GO:0005515	protein binding	IPI	J:254528
Molecular Function	GO:0005515	protein binding	IPI	J:251563
Cellular Component	GO:0030424	axon	IDA	J:147119
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:147119
Cellular Component	GO:0005576	extracellular region	IDA	J:163254
Cellular Component	GO:0005576	extracellular region	IDA	J:149558
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:116059
Cellular Component	GO:0043025	neuronal cell body	IDA	J:147119
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:1905370	serine-type endopeptidase complex	ISO	J:164563
Cellular Component	GO:0106139	symbiont cell surface	ISO	J:164563
Biological Process	GO:0001905	activation of membrane attack complex	IMP	J:165433
Biological Process	GO:0001525	angiogenesis	IMP	J:240426
Biological Process	GO:0046034	ATP metabolic process	IMP	J:235549
Biological Process	GO:0060348	bone development	IGI	J:156611
Biological Process	GO:0051216	cartilage development	IGI	J:156611
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IGI	J:156611
Biological Process	GO:0006956	complement activation	ISO	J:164563
Biological Process	GO:0006956	complement activation	IBA	J:265628
Biological Process	GO:0006956	complement activation	IMP	J:240426
Biological Process	GO:0006956	complement activation	IGI	J:163836
Biological Process	GO:0006956	complement activation	IDA	J:163254
Biological Process	GO:0006956	complement activation	IMP	J:149983
Biological Process	GO:0006956	complement activation	IDA	J:149558
Biological Process	GO:0006956	complement activation	IMP	J:125991
Biological Process	GO:0006956	complement activation	IMP	J:125860
Biological Process	GO:0006956	complement activation	IMP	J:110085
Biological Process	GO:0006957	complement activation, alternative pathway	IMP	J:250675
Biological Process	GO:0006957	complement activation, alternative pathway	IGI	J:250675
Biological Process	GO:0006957	complement activation, alternative pathway	IGI	J:156611
Biological Process	GO:0008340	determination of adult lifespan	IMP	J:240426
Biological Process	GO:0010467	gene expression	IMP	J:218073
Biological Process	GO:0010467	gene expression	IMP	J:204297
Biological Process	GO:0010467	gene expression	IMP	J:110085
Biological Process	GO:0032835	glomerulus development	IGI	J:163836
Biological Process	GO:0032835	glomerulus development	IMP	J:125860
Biological Process	GO:0032835	glomerulus development	IGI	J:111031
Biological Process	GO:0032835	glomerulus development	IMP	J:110085
Biological Process	GO:0002434	immune complex clearance	IGI	J:163836
Biological Process	GO:0006955	immune response	IMP	J:149983
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0016064	immunoglobulin mediated immune response	IGI	J:156611
Biological Process	GO:0006954	inflammatory response	IMP	J:254528
Biological Process	GO:0006954	inflammatory response	IMP	J:235549
Biological Process	GO:0006954	inflammatory response	IGI	J:156611
Biological Process	GO:0090594	inflammatory response to wounding	IGI	J:185883
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0001822	kidney development	IMP	J:125860
Biological Process	GO:0001822	kidney development	IGI	J:111031
Biological Process	GO:0032042	mitochondrial DNA metabolic process	IMP	J:275920
Biological Process	GO:0140053	mitochondrial gene expression	IMP	J:235549
Biological Process	GO:0007005	mitochondrion organization	IMP	J:275920
Biological Process	GO:0070487	monocyte aggregation	IMP	J:254528
Biological Process	GO:0050905	neuromuscular process	IMP	J:251563
Biological Process	GO:0001780	neutrophil homeostasis	IGI	J:111031
Biological Process	GO:0002251	organ or tissue specific immune response	IGI	J:163836
Biological Process	GO:0051640	organelle localization	IMP	J:125991
Biological Process	GO:0046530	photoreceptor cell differentiation	IMP	J:275920
Biological Process	GO:0046530	photoreceptor cell differentiation	IMP	J:235549
Biological Process	GO:0070527	platelet aggregation	IMP	J:240426
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0030449	regulation of complement activation	ISO	J:155856
Biological Process	GO:0030449	regulation of complement activation	IMP	J:145047
Biological Process	GO:0030449	regulation of complement activation	ISO	J:218542
Biological Process	GO:0030451	regulation of complement activation, alternative pathway	ISO	J:164563
Biological Process	GO:1903659	regulation of complement-dependent cytotoxicity	ISO	J:218542
Biological Process	GO:0034097	response to cytokine	IDA	J:147119
Biological Process	GO:0002021	response to dietary excess	IMP	J:223294
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:275920
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:240426
Biological Process	GO:0060041	retina development in camera-type eye	IGI	J:240426
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:240426
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:125991
Biological Process	GO:0003406	retinal pigment epithelium development	IMP	J:223294
Biological Process	GO:0003406	retinal pigment epithelium development	IMP	J:204297
Biological Process	GO:0046548	retinal rod cell development	IMP	J:125991
Biological Process	GO:0035886	vascular associated smooth muscle cell differentiation	IMP	J:240426
Biological Process	GO:0035886	vascular associated smooth muscle cell differentiation	IGI	J:240426
Biological Process	GO:0007601	visual perception	IMP	J:223294
Biological Process	GO:0007601	visual perception	IMP	J:125991
Biological Process	GO:0007601	visual perception	IMP	J:125860

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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