GO Annotations Graph

• Symbol: Chga
• Name: chromogranin A
• ID: MGI:88394

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:105360
Molecular Function	GO:0005515	protein binding	IPI	J:102191
Molecular Function	GO:0005515	protein binding	IPI	J:102191
Cellular Component	GO:0042583	chromaffin granule	ISO	J:155856
Cellular Component	GO:0042583	chromaffin granule	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0098992	neuronal dense core vesicle	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0030141	secretory granule	ISO	J:155856
Biological Process	GO:0086030	adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation	ISO	J:155856
Biological Process	GO:0086030	adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation	IBA	J:265628
Biological Process	GO:0042742	defense response to bacterium	IBA	J:265628
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ISO	J:164563
Biological Process	GO:0045576	mast cell activation	ISO	J:164563
Biological Process	GO:0002551	mast cell chemotaxis	ISO	J:164563
Biological Process	GO:0043303	mast cell degranulation	ISO	J:164563
Biological Process	GO:0033604	negative regulation of catecholamine secretion	ISO	J:164563
Biological Process	GO:0033604	negative regulation of catecholamine secretion	IBA	J:265628
Biological Process	GO:0046676	negative regulation of insulin secretion	IBA	J:265628
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:155856
Biological Process	GO:0006996	organelle organization	ISO	J:155856
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0060452	positive regulation of cardiac muscle contraction	ISO	J:155856
Biological Process	GO:2000707	positive regulation of dense core granule biogenesis	IDA	J:219078
Biological Process	GO:1900738	positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:1901899	positive regulation of relaxation of cardiac muscle	ISO	J:155856
Biological Process	GO:0045907	positive regulation of vasoconstriction	ISO	J:155856
Biological Process	GO:0033366	protein localization to secretory granule	IDA	J:102191
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0002026	regulation of the force of heart contraction	ISO	J:155856