GO Annotations Graph

• Symbol: Chrm2
• Name: cholinergic receptor, muscarinic 2, cardiac
• ID: MGI:88397

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1990763	arrestin family protein binding	ISO	J:164563
Molecular Function	GO:0016907	G protein-coupled acetylcholine receptor activity	ISO	J:164563
Molecular Function	GO:0016907	G protein-coupled acetylcholine receptor activity	ISO	J:155856
Molecular Function	GO:0016907	G protein-coupled acetylcholine receptor activity	IBA	J:265628
Molecular Function	GO:0016907	G protein-coupled acetylcholine receptor activity	IMP	J:53061
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004993	G protein-coupled serotonin receptor activity	IBA	J:265628
Cellular Component	GO:0032279	asymmetric synapse	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0098981	cholinergic synapse	EXP	J:75157
Cellular Component	GO:0098981	cholinergic synapse	IMP	J:75157
Cellular Component	GO:0098981	cholinergic synapse	IMP	J:75157
Cellular Component	GO:0098981	cholinergic synapse	IMP	J:75157
Cellular Component	GO:0098981	cholinergic synapse	EXP	J:75157
Cellular Component	GO:0098981	cholinergic synapse	EXP	J:75157
Cellular Component	GO:0098981	cholinergic synapse	EXP	J:75157
Cellular Component	GO:0098981	cholinergic synapse	EXP	J:75157
Cellular Component	GO:0098981	cholinergic synapse	EXP	J:75157
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0032280	symmetric synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0007197	adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	IMP	J:53061
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IBA	J:265628
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:75157
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:75157
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:75157
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:75157
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:75157
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:75157
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:75157
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:75157
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:75157
Biological Process	GO:0008016	regulation of heart contraction	IEA	J:72247
Biological Process	GO:0006940	regulation of smooth muscle contraction	ISO	J:155856
Biological Process	GO:0006940	regulation of smooth muscle contraction	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:60000