GO Annotations Graph

• Symbol: Vsx2
• Name: visual system homeobox 2
• ID: MGI:88401

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:45398
Molecular Function	GO:0005515	protein binding	IPI	J:97559
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:97559
Cellular Component	GO:0005737	cytoplasm	IDA	J:149456
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:57340
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:149456
Cellular Component	GO:0005634	nucleus	IDA	J:97559
Biological Process	GO:0043010	camera-type eye development	IGI	J:94374
Biological Process	GO:0045165	cell fate commitment	IMP	J:94374
Biological Process	GO:0008283	cell population proliferation	IMP	J:32083
Biological Process	GO:0008283	cell population proliferation	IMP	J:104265
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	IMP	J:104265
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:104265
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:32083
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:97559
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0050896	response to stimulus	IEA	J:60000
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	IMP	J:119026
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	IMP	J:32083
Biological Process	GO:0060040	retinal bipolar neuron differentiation	IMP	J:32083
Biological Process	GO:0007601	visual perception	IEA	J:60000