GO Annotations Graph

• Symbol: Col18a1
• Name: collagen, type XVIII, alpha 1
• ID: MGI:88451

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	IBA	J:265628
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	RCA	J:265607
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	RCA	J:265604
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:121136
Cellular Component	GO:0005604	basement membrane	IDA	J:92842
Cellular Component	GO:0005604	basement membrane	IDA	J:28734
Cellular Component	GO:0005604	basement membrane	IDA	J:154510
Cellular Component	GO:0005604	basement membrane	IDA	J:92842
Cellular Component	GO:0005604	basement membrane	IDA	J:139122
Cellular Component	GO:0005604	basement membrane	IDA	J:81999
Cellular Component	GO:0005604	basement membrane	IDA	J:92842
Cellular Component	GO:0005581	collagen trimer	IBA	J:265628
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0031012	extracellular matrix	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IMP	J:75861
Biological Process	GO:0001525	angiogenesis	IDA	J:91211
Biological Process	GO:0043534	blood vessel endothelial cell migration	IDA	J:91211
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0030199	collagen fibril organization	IBA	J:265628
Biological Process	GO:0072577	endothelial cell apoptotic process	IDA	J:91211
Biological Process	GO:0001886	endothelial cell morphogenesis	IDA	J:91211
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:92842
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:92842
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:92842
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:92842
Biological Process	GO:0030903	notochord development	IBA	J:265628
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	IDA	J:91211
Biological Process	GO:2000353	positive regulation of endothelial cell apoptotic process	IDA	J:91211
Biological Process	GO:1905564	positive regulation of vascular endothelial cell proliferation	IDA	J:91211
Biological Process	GO:0001501	skeletal system development	IBA	J:265628
Biological Process	GO:0101023	vascular endothelial cell proliferation	IDA	J:91211