GO Annotations Graph

• Symbol: Comp
• Name: cartilage oligomeric matrix protein
• ID: MGI:88469

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0036122	BMP binding	IPI	J:183590
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005518	collagen binding	ISO	J:164563
Molecular Function	GO:0005201	extracellular matrix structural constituent	ISO	J:155856
Molecular Function	GO:0001968	fibronectin binding	ISO	J:155856
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	ISO	J:164563
Molecular Function	GO:0008201	heparin binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	IPI	J:250705
Molecular Function	GO:0002020	protease binding	IPI	J:204646
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:204646
Molecular Function	GO:0005515	protein binding	IPI	J:159707
Molecular Function	GO:0005515	protein binding	IPI	J:121129
Molecular Function	GO:0043394	proteoglycan binding	ISO	J:255711
Molecular Function	GO:0005499	vitamin D binding	ISO	J:155856
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IDA	J:314913
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IDA	J:125086
Cellular Component	GO:0005615	extracellular space	IDA	J:246348
Cellular Component	GO:0032991	protein-containing complex	IDA	J:225913
Biological Process	GO:0006915	apoptotic process	IMP	J:125086
Biological Process	GO:0048844	artery morphogenesis	IMP	J:250705
Biological Process	GO:0007596	blood coagulation	IMP	J:225913
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:183590
Biological Process	GO:0098868	bone growth	IMP	J:125086
Biological Process	GO:0030282	bone mineralization	IMP	J:250705
Biological Process	GO:0060349	bone morphogenesis	IGI	J:139384
Biological Process	GO:0051216	cartilage development	IMP	J:125086
Biological Process	GO:0051216	cartilage development	IMP	J:201073
Biological Process	GO:0051216	cartilage development	IGI	J:139384
Biological Process	GO:0051216	cartilage development	IMP	J:201073
Biological Process	GO:1990079	cartilage homeostasis	ISO	J:164563
Biological Process	GO:1990079	cartilage homeostasis	IDA	J:314913
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0090398	cellular senescence	IMP	J:238972
Biological Process	GO:0002063	chondrocyte development	IMP	J:206511
Biological Process	GO:0002063	chondrocyte development	IMP	J:125086
Biological Process	GO:0035988	chondrocyte proliferation	IMP	J:125086
Biological Process	GO:0035988	chondrocyte proliferation	IMP	J:206511
Biological Process	GO:0035988	chondrocyte proliferation	IGI	J:139384
Biological Process	GO:0030199	collagen fibril organization	IMP	J:154984
Biological Process	GO:0030199	collagen fibril organization	IMP	J:246348
Biological Process	GO:0030199	collagen fibril organization	IMP	J:209751
Biological Process	GO:0003416	endochondral bone growth	IMP	J:159707
Biological Process	GO:0003417	growth plate cartilage development	IGI	J:139384
Biological Process	GO:0003417	growth plate cartilage development	IMP	J:136242
Biological Process	GO:0003417	growth plate cartilage development	IGI	J:136242
Biological Process	GO:0003417	growth plate cartilage development	IGI	J:136242
Biological Process	GO:0003417	growth plate cartilage development	IGI	J:136242
Biological Process	GO:0003417	growth plate cartilage development	IMP	J:125086
Biological Process	GO:0060173	limb development	ISO	J:164563
Biological Process	GO:0060173	limb development	IMP	J:125086
Biological Process	GO:0060173	limb development	IMP	J:206511
Biological Process	GO:0035264	multicellular organism growth	IMP	J:125086
Biological Process	GO:0035264	multicellular organism growth	IMP	J:206511
Biological Process	GO:0055001	muscle cell development	IMP	J:209751
Biological Process	GO:0055001	muscle cell development	IMP	J:154984
Biological Process	GO:0050881	musculoskeletal movement	IMP	J:154984
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:1900047	negative regulation of hemostasis	IMP	J:225913
Biological Process	GO:0050905	neuromuscular process	IMP	J:209751
Biological Process	GO:0001503	ossification	IMP	J:250705
Biological Process	GO:0001503	ossification	IMP	J:183590
Biological Process	GO:0070527	platelet aggregation	IMP	J:225913
Biological Process	GO:1902732	positive regulation of chondrocyte proliferation	IMP	J:121129
Biological Process	GO:0051260	protein homooligomerization	IDA	J:314913
Biological Process	GO:0051260	protein homooligomerization	ISO	J:164563
Biological Process	GO:0016485	protein processing	IMP	J:225913
Biological Process	GO:0009306	protein secretion	IMP	J:246348
Biological Process	GO:0030500	regulation of bone mineralization	IMP	J:183590
Biological Process	GO:0010468	regulation of gene expression	IMP	J:206511
Biological Process	GO:0010468	regulation of gene expression	IMP	J:238972
Biological Process	GO:0006986	response to unfolded protein	IMP	J:125086
Biological Process	GO:0001501	skeletal system development	IGI	J:139384
Biological Process	GO:0043588	skin development	IMP	J:246348
Biological Process	GO:0035989	tendon development	IMP	J:209751
Biological Process	GO:0035989	tendon development	IMP	J:154984
Biological Process	GO:0097084	vascular associated smooth muscle cell development	IMP	J:183590
Biological Process	GO:0014829	vascular associated smooth muscle contraction	IMP	J:238972