GO Annotations Graph

• Symbol: Crp
• Name: C-reactive protein, pentraxin-related
• ID: MGI:88512

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0015485	cholesterol binding	ISO	J:155856
Molecular Function	GO:0001849	complement component C1q complex binding	ISO	J:164563
Molecular Function	GO:0001849	complement component C1q complex binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0030169	low-density lipoprotein particle binding	ISO	J:155856
Molecular Function	GO:0030169	low-density lipoprotein particle binding	ISO	J:164563
Molecular Function	GO:0030169	low-density lipoprotein particle binding	IBA	J:265628
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0030175	filopodium	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Biological Process	GO:0006953	acute-phase response	IEA	J:60000
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:155856
Biological Process	GO:0006958	complement activation, classical pathway	ISO	J:155856
Biological Process	GO:0045087	innate immune response	IBA	J:265628
Biological Process	GO:0010888	negative regulation of lipid storage	ISO	J:164563
Biological Process	GO:0010745	negative regulation of macrophage derived foam cell differentiation	ISO	J:164563
Biological Process	GO:0032945	negative regulation of mononuclear cell proliferation	ISO	J:164563
Biological Process	GO:0032929	negative regulation of superoxide anion generation	ISO	J:155856
Biological Process	GO:1900006	positive regulation of dendrite development	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	ISO	J:155856
Biological Process	GO:0032930	positive regulation of superoxide anion generation	ISO	J:164563
Biological Process	GO:0051258	protein polymerization	ISO	J:155856
Biological Process	GO:0032677	regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0010988	regulation of low-density lipoprotein particle clearance	ISO	J:155856
Biological Process	GO:0042310	vasoconstriction	ISO	J:164563
Biological Process	GO:0042060	wound healing	ISO	J:155856