GO Annotations Graph

• Symbol: Cr1l
• Name: complement C3b/C4b receptor 1 like
• ID: MGI:88513

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001851	complement component C3b binding	ISO	J:164563
Molecular Function	GO:0004877	complement component C3b receptor activity	ISO	J:164563
Molecular Function	GO:0001855	complement component C4b binding	ISO	J:164563
Molecular Function	GO:0001861	complement component C4b receptor activity	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:163254
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:163254
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:145047
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0044853	plasma membrane raft	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0071456	cellular response to hypoxia	IDA	J:163254
Biological Process	GO:0006956	complement activation	IMP	J:163254
Biological Process	GO:0006958	complement activation, classical pathway	IEA	J:60000
Biological Process	GO:0007565	female pregnancy	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0001701	in utero embryonic development	IGI	J:145047
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045916	negative regulation of complement activation	ISO	J:155856
Biological Process	GO:0045916	negative regulation of complement activation	IMP	J:59432
Biological Process	GO:0045959	negative regulation of complement activation, classical pathway	IBA	J:265628
Biological Process	GO:0030449	regulation of complement activation	TAS	J:72683
Biological Process	GO:0030449	regulation of complement activation	IMP	J:145047
Biological Process	GO:0030449	regulation of complement activation	ISO	J:218542
Biological Process	GO:1903659	regulation of complement-dependent cytotoxicity	ISO	J:218542
Biological Process	GO:0002456	T cell mediated immunity	IBA	J:265628