GO Annotations Graph

• Symbol: Cryaa
• Name: crystallin, alpha A
• ID: MGI:88515

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:149371
Molecular Function	GO:0005515	protein binding	IPI	J:106028
Molecular Function	GO:0005515	protein binding	IPI	J:132296
Molecular Function	GO:0005212	structural constituent of eye lens	TAS	J:86897
Molecular Function	GO:0005198	structural molecule activity	ISO	J:164563
Molecular Function	GO:0051082	unfolded protein binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:82601
Cellular Component	GO:0005737	cytoplasm	IDA	J:51620
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0007015	actin filament organization	IMP	J:112248
Biological Process	GO:0006915	apoptotic process	IMP	J:132296
Biological Process	GO:0060561	apoptotic process involved in morphogenesis	IGI	J:106028
Biological Process	GO:0043010	camera-type eye development	IGI	J:86897
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	IMP	J:132296
Biological Process	GO:0002088	lens development in camera-type eye	IBA	J:265628
Biological Process	GO:0002088	lens development in camera-type eye	IMP	J:72928
Biological Process	GO:0002088	lens development in camera-type eye	IGI	J:106028
Biological Process	GO:0002088	lens development in camera-type eye	IMP	J:106028
Biological Process	GO:0002088	lens development in camera-type eye	IMP	J:38210
Biological Process	GO:0070309	lens fiber cell morphogenesis	IMP	J:132296
Biological Process	GO:0070309	lens fiber cell morphogenesis	IMP	J:112248
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	IMP	J:34933
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	IMP	J:112248
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	IMP	J:112248
Biological Process	GO:0007017	microtubule-based process	IMP	J:82601
Biological Process	GO:0007005	mitochondrion organization	IMP	J:112248
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:132494
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	IGI	J:106028
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:125299
Biological Process	GO:0032387	negative regulation of intracellular transport	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	IMP	J:51620
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IMP	J:132296
Biological Process	GO:0006457	protein folding	ISO	J:155856
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0042542	response to hydrogen peroxide	ISO	J:155856
Biological Process	GO:0042542	response to hydrogen peroxide	IMP	J:121617
Biological Process	GO:0001666	response to hypoxia	IMP	J:132494
Biological Process	GO:0070141	response to UV-A	IMP	J:51620
Biological Process	GO:0007021	tubulin complex assembly	IMP	J:111251
Biological Process	GO:0007601	visual perception	ISO	J:164563