GO Annotations Graph

• Symbol: Ctsg
• Name: cathepsin G
• ID: MGI:88563

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0089720	caspase binding	ISO	J:164563
Molecular Function	GO:0008201	heparin binding	ISO	J:73065
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:79876
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0008236	serine-type peptidase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0030141	secretory granule	ISO	J:73065
Biological Process	GO:0019731	antibacterial humoral response	ISO	J:164563
Biological Process	GO:0098786	biofilm matrix disassembly	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0042742	defense response to bacterium	IEA	J:60000
Biological Process	GO:0050832	defense response to fungus	IGI	J:77597
Biological Process	GO:0050832	defense response to fungus	IMP	J:77597
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:151389
Biological Process	GO:0002548	monocyte chemotaxis	ISO	J:164563
Biological Process	GO:0050868	negative regulation of T cell activation	ISO	J:164563
Biological Process	GO:0042119	neutrophil activation	ISO	J:164563
Biological Process	GO:0070946	neutrophil-mediated killing of gram-positive bacterium	IMP	J:151389
Biological Process	GO:0030168	platelet activation	ISO	J:164563
Biological Process	GO:0050778	positive regulation of immune response	IGI	J:77597
Biological Process	GO:0050778	positive regulation of immune response	IMP	J:77597
Biological Process	GO:1901731	positive regulation of platelet aggregation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0016485	protein processing	ISO	J:164563
Biological Process	GO:0006508	proteolysis	ISO	J:73065
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:77597
Biological Process	GO:0032496	response to lipopolysaccharide	IGI	J:77597