GO Annotations Graph

• Symbol: Cyp1a1
• Name: cytochrome P450, family 1, subfamily a, polypeptide 1
• ID: MGI:88588

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008391	arachidonic acid monooxygenase activity	ISO	J:164563
Molecular Function	GO:0070330	aromatase activity	IEA	J:72245
Molecular Function	GO:0003824	catalytic activity	ISO	J:155856
Molecular Function	GO:0032451	demethylase activity	ISO	J:155856
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0101020	estrogen 16-alpha-hydroxylase activity	ISO	J:164563
Molecular Function	GO:0101021	estrogen 2-hydroxylase activity	ISO	J:164563
Molecular Function	GO:0016711	flavonoid 3'-monooxygenase activity	ISO	J:155856
Molecular Function	GO:0020037	heme binding	IEA	J:72247
Molecular Function	GO:0030544	Hsp70 protein binding	ISO	J:155856
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:155856
Molecular Function	GO:0106256	hydroperoxy icosatetraenoate dehydratase activity	IEA	J:72245
Molecular Function	GO:0005506	iron ion binding	IEA	J:72247
Molecular Function	GO:0120319	long-chain fatty acid omega-1 hydroxylase activity	ISO	J:164563
Molecular Function	GO:0102033	long-chain fatty acid omega-hydroxylase activity	ISO	J:164563
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	ISO	J:155856
Molecular Function	GO:0004497	monooxygenase activity	IBA	J:265628
Molecular Function	GO:0004497	monooxygenase activity	IDA	J:86914
Molecular Function	GO:0016491	oxidoreductase activity	ISO	J:155856
Molecular Function	GO:0016491	oxidoreductase activity	ISO	J:155856
Molecular Function	GO:0016491	oxidoreductase activity	ISO	J:164563
Molecular Function	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	ISO	J:155856
Molecular Function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	J:72247
Molecular Function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IDA	J:16172
Molecular Function	GO:0008395	steroid hydroxylase activity	ISO	J:155856
Molecular Function	GO:0070576	vitamin D 24-hydroxylase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Biological Process	GO:0042904	9-cis-retinoic acid biosynthetic process	ISO	J:155856
Biological Process	GO:0009308	amine metabolic process	IMP	J:120001
Biological Process	GO:0071407	cellular response to organic cyclic compound	ISO	J:200218
Biological Process	GO:0009804	coumarin metabolic process	ISO	J:155856
Biological Process	GO:0019341	dibenzo-p-dioxin catabolic process	ISO	J:155856
Biological Process	GO:0008210	estrogen metabolic process	ISO	J:164563
Biological Process	GO:0006631	fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0009812	flavonoid metabolic process	ISO	J:155856
Biological Process	GO:0046483	heterocycle metabolic process	IMP	J:120001
Biological Process	GO:0050665	hydrogen peroxide biosynthetic process	IMP	J:88957
Biological Process	GO:0017143	insecticide metabolic process	ISO	J:155856
Biological Process	GO:0002933	lipid hydroxylation	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0006778	porphyrin-containing compound metabolic process	ISO	J:155856
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:155856
Biological Process	GO:0009636	response to toxic substance	IMP	J:135804
Biological Process	GO:0042572	retinol metabolic process	ISO	J:164563
Biological Process	GO:0006694	steroid biosynthetic process	IEA	J:60000
Biological Process	GO:0008202	steroid metabolic process	ISO	J:164563
Biological Process	GO:0009404	toxin metabolic process	IMP	J:122123
Biological Process	GO:0006805	xenobiotic metabolic process	ISO	J:164563