GO Annotations Graph

• Symbol: Frzb
• Name: frizzled-related protein
• ID: MGI:892032

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:147775
Molecular Function	GO:0005515	protein binding	IPI	J:39275
Molecular Function	GO:0017147	Wnt-protein binding	IDA	J:40600
Molecular Function	GO:0017147	Wnt-protein binding	IBA	J:265628
Molecular Function	GO:0017147	Wnt-protein binding	IPI	J:121773
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	NAS	J:40600
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:122585
Biological Process	GO:0060029	convergent extension involved in organogenesis	IGI	J:122585
Biological Process	GO:0002064	epithelial cell development	IDA	J:152099
Biological Process	GO:0070365	hepatocyte differentiation	IDA	J:152099
Biological Process	GO:0042472	inner ear morphogenesis	IDA	J:143184
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:143184
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IGI	J:156721
Biological Process	GO:0061037	negative regulation of cartilage development	IGI	J:143184
Biological Process	GO:0010721	negative regulation of cell development	IDA	J:152099
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0070367	negative regulation of hepatocyte differentiation	IDA	J:152099
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	IDA	J:40600
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	IGI	J:122585
Biological Process	GO:0014033	neural crest cell differentiation	IEP	J:53153
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:73065
Biological Process	GO:0045600	positive regulation of fat cell differentiation	ISO	J:78619
Biological Process	GO:0061053	somite development	IEP	J:53153
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000