GO Annotations Graph

• Symbol: Bche
• Name: butyrylcholinesterase
• ID: MGI:894278

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003990	acetylcholinesterase activity	IDA	J:156049
Molecular Function	GO:0003990	acetylcholinesterase activity	IBA	J:265628
Molecular Function	GO:0052689	carboxylic ester hydrolase activity	IEA	J:60000
Molecular Function	GO:0033265	choline binding	ISO	J:155856
Molecular Function	GO:0004104	cholinesterase activity	ISO	J:155856
Molecular Function	GO:0004104	cholinesterase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:29481
Cellular Component	GO:0005788	endoplasmic reticulum lumen	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005641	nuclear envelope lumen	IDA	J:29481
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0006581	acetylcholine catabolic process	IBA	J:265628
Biological Process	GO:0019695	choline metabolic process	ISO	J:155856
Biological Process	GO:0019695	choline metabolic process	IBA	J:265628
Biological Process	GO:0007612	learning	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0050805	negative regulation of synaptic transmission	ISO	J:155856
Biological Process	GO:0014016	neuroblast differentiation	ISO	J:155856
Biological Process	GO:0043279	response to alkaloid	ISO	J:155856
Biological Process	GO:0051593	response to folic acid	ISO	J:155856
Biological Process	GO:0051384	response to glucocorticoid	ISO	J:155856
Biological Process	GO:0007584	response to nutrient	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856