GO Annotations Graph

• Symbol: Mtr
• Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
• ID: MGI:894292

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016597	amino acid binding	ISO	J:155856
Molecular Function	GO:0031419	cobalamin binding	IEA	J:60000
Molecular Function	GO:0031419	cobalamin binding	IEA	J:72247
Molecular Function	GO:0005542	folic acid binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008705	methionine synthase activity	ISO	J:164563
Molecular Function	GO:0008705	methionine synthase activity	ISO	J:155856
Molecular Function	GO:0008705	methionine synthase activity	IBA	J:265628
Molecular Function	GO:0008705	methionine synthase activity	IMP	J:67384
Molecular Function	GO:0008705	methionine synthase activity	IMP	J:67384
Molecular Function	GO:0008168	methyltransferase activity	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Biological Process	GO:0008652	amino acid biosynthetic process	IEA	J:60000
Biological Process	GO:0031103	axon regeneration	ISO	J:155856
Biological Process	GO:0044237	cellular metabolic process	IEA	J:72247
Biological Process	GO:0071732	cellular response to nitric oxide	ISO	J:155856
Biological Process	GO:0009235	cobalamin metabolic process	ISO	J:164563
Biological Process	GO:0009235	cobalamin metabolic process	IMP	J:67384
Biological Process	GO:0050667	homocysteine metabolic process	ISO	J:155856
Biological Process	GO:0050667	homocysteine metabolic process	IBA	J:265628
Biological Process	GO:0009086	methionine biosynthetic process	ISO	J:155856
Biological Process	GO:0009086	methionine biosynthetic process	ISO	J:164563
Biological Process	GO:0009086	methionine biosynthetic process	IBA	J:265628
Biological Process	GO:0009086	methionine biosynthetic process	IMP	J:67384
Biological Process	GO:0006555	methionine metabolic process	ISO	J:155856
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0006479	protein methylation	ISO	J:155856
Biological Process	GO:0042558	pteridine-containing compound metabolic process	IEA	J:72247
Biological Process	GO:0048678	response to axon injury	ISO	J:155856
Biological Process	GO:0046653	tetrahydrofolate metabolic process	ISO	J:155856
Biological Process	GO:0046653	tetrahydrofolate metabolic process	IBA	J:265628