GO Annotations Graph

• Symbol: Pirb
• Name: paired Ig-like receptor B
• ID: MGI:894311

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001540	amyloid-beta binding	IDA	J:201126
Molecular Function	GO:0001540	amyloid-beta binding	IMP	J:201126
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:164563
Molecular Function	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity	ISO	J:164563
Molecular Function	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity	ISO	J:164563
Molecular Function	GO:0032396	inhibitory MHC class I receptor activity	ISO	J:164563
Molecular Function	GO:0032396	inhibitory MHC class I receptor activity	IBA	J:265628
Molecular Function	GO:0042288	MHC class I protein binding	ISO	J:164563
Molecular Function	GO:0042288	MHC class I protein binding	ISO	J:164563
Molecular Function	GO:0032393	MHC class I receptor activity	ISO	J:164563
Molecular Function	GO:0023029	MHC class Ib protein binding	ISO	J:164563
Molecular Function	GO:0023029	MHC class Ib protein binding	ISO	J:164563
Molecular Function	GO:0023025	MHC class Ib protein complex binding	ISO	J:164563
Molecular Function	GO:0023025	MHC class Ib protein complex binding	ISO	J:164563
Molecular Function	GO:0032394	MHC class Ib receptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:201126
Molecular Function	GO:0005515	protein binding	IPI	J:186638
Molecular Function	GO:0005515	protein binding	IPI	J:201126
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:201126
Molecular Function	GO:0008157	protein phosphatase 1 binding	ISO	J:164563
Molecular Function	GO:0008157	protein phosphatase 1 binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	IPI	J:201126
Molecular Function	GO:0042169	SH2 domain binding	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0001782	B cell homeostasis	IMP	J:76770
Biological Process	GO:0019724	B cell mediated immunity	IMP	J:76770
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IMP	J:76770
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0007611	learning or memory	IGI	J:201126
Biological Process	GO:0043011	myeloid dendritic cell differentiation	IMP	J:76770
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	ISO	J:164563
Biological Process	GO:0051248	negative regulation of protein metabolic process	IGI	J:201126
Biological Process	GO:1900454	positive regulation of long-term synaptic depression	IGI	J:201126
Biological Process	GO:0035307	positive regulation of protein dephosphorylation	IGI	J:201126
Biological Process	GO:1900271	regulation of long-term synaptic potentiation	IGI	J:201126