GO Annotations Graph

• Symbol: Prdx6
• Name: peroxiredoxin 6
• ID: MGI:894320

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity	ISO	J:155856
Molecular Function	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity	IMP	J:231458
Molecular Function	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity	ISO	J:164563
Molecular Function	GO:0016209	antioxidant activity	IEA	J:72247
Molecular Function	GO:0016209	antioxidant activity	IEA	J:60000
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	ISO	J:164563
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0004602	glutathione peroxidase activity	ISO	J:155856
Molecular Function	GO:0004602	glutathione peroxidase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0004601	peroxidase activity	IMP	J:84376
Molecular Function	GO:0051920	peroxiredoxin activity	IEA	J:72247
Molecular Function	GO:0004623	phospholipase A2 activity	IMP	J:231458
Molecular Function	GO:0004623	phospholipase A2 activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:197839
Molecular Function	GO:0008379	thioredoxin peroxidase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:84376
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Biological Process	GO:0032060	bleb assembly	IMP	J:120291
Biological Process	GO:0045454	cell redox homeostasis	IBA	J:265628
Biological Process	GO:0098869	cellular oxidant detoxification	ISO	J:164563
Biological Process	GO:0046475	glycerophospholipid catabolic process	ISO	J:164563
Biological Process	GO:0042744	hydrogen peroxide catabolic process	ISO	J:155856
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0048026	positive regulation of mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0006979	response to oxidative stress	ISO	J:164563
Biological Process	GO:0000302	response to reactive oxygen species	IMP	J:84376