GO Annotations Graph

• Symbol: Pick1
• Name: protein interacting with C kinase 1
• ID: MGI:894645

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	ISO	J:155856
Molecular Function	GO:0071933	Arp2/3 complex binding	ISO	J:155856
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:155856
Molecular Function	GO:0035256	G protein-coupled glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0001664	G protein-coupled receptor binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0140090	membrane curvature sensor activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005543	phospholipid binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:197677
Molecular Function	GO:0005515	protein binding	IPI	J:51893
Molecular Function	GO:0005515	protein binding	IPI	J:113830
Molecular Function	GO:0005515	protein binding	IPI	J:212850
Molecular Function	GO:0005515	protein binding	IPI	J:233657
Molecular Function	GO:0005515	protein binding	IPI	J:207532
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0005080	protein kinase C binding	IPI	J:41185
Molecular Function	GO:0005080	protein kinase C binding	IPI	J:113830
Molecular Function	GO:0005080	protein kinase C binding	ISO	J:155856
Molecular Function	GO:0005080	protein kinase C binding	IBA	J:265628
Molecular Function	GO:0005102	signaling receptor binding	IPI	J:51893
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Molecular Function	GO:0005484	SNAP receptor activity	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:41185
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:41185
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IDA	J:85668
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:41185
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IDA	J:207532
Cellular Component	GO:0098842	postsynaptic early endosome	ISO	J:155856
Cellular Component	GO:0098842	postsynaptic early endosome	IBA	J:265628
Cellular Component	GO:0098843	postsynaptic endocytic zone	ISO	J:155856
Cellular Component	GO:0099572	postsynaptic specialization	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:51893
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	IBA	J:265628
Cellular Component	GO:0032588	trans-Golgi network membrane	IBA	J:265628
Biological Process	GO:0036294	cellular response to decreased oxygen levels	ISO	J:155856
Biological Process	GO:0042149	cellular response to glucose starvation	ISO	J:155856
Biological Process	GO:0097062	dendritic spine maintenance	ISO	J:155856
Biological Process	GO:0097062	dendritic spine maintenance	IBA	J:265628
Biological Process	GO:0097061	dendritic spine organization	ISO	J:155856
Biological Process	GO:0021782	glial cell development	ISO	J:155856
Biological Process	GO:0006886	intracellular protein transport	IBA	J:265628
Biological Process	GO:0035556	intracellular signal transduction	NAS	J:41185
Biological Process	GO:0060292	long-term synaptic depression	ISO	J:155856
Biological Process	GO:0015844	monoamine transport	ISO	J:164563
Biological Process	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	ISO	J:155856
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0002092	positive regulation of receptor internalization	ISO	J:155856
Biological Process	GO:0002092	positive regulation of receptor internalization	IBA	J:265628
Biological Process	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0006605	protein targeting	IDA	J:85668
Biological Process	GO:0043113	receptor clustering	IDA	J:51893
Biological Process	GO:0043113	receptor clustering	ISO	J:155856
Biological Process	GO:0043113	receptor clustering	IBA	J:265628
Biological Process	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	IBA	J:265628
Biological Process	GO:0050796	regulation of insulin secretion	ISO	J:164563
Biological Process	GO:2000312	regulation of kainate selective glutamate receptor activity	ISO	J:155856
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	ISO	J:155856
Biological Process	GO:0050803	regulation of synapse structure or activity	NAS	J:51893