GO Annotations Graph

• Symbol: Xrn2
• Name: 5'-3' exoribonuclease 2
• ID: MGI:894687

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	ISO	J:164563
Molecular Function	GO:0008409	5'-3' exonuclease activity	ISO	J:164563
Molecular Function	GO:0004534	5'-3' RNA exonuclease activity	NAS	J:23616
Molecular Function	GO:0004534	5'-3' RNA exonuclease activity	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0004527	exonuclease activity	IEA	J:72247
Molecular Function	GO:0004527	exonuclease activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:185950
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0001147	transcription termination site sequence-specific DNA binding	ISO	J:164563
Cellular Component	GO:0016235	aggresome	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0006310	DNA recombination	NAS	J:23616
Biological Process	GO:0006281	DNA repair	NAS	J:23616
Biological Process	GO:0006353	DNA-templated transcription termination	IEA	J:60000
Biological Process	GO:0007017	microtubule-based process	TAS	J:23616
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	IBA	J:265628
Biological Process	GO:0006139	nucleobase-containing compound metabolic process	IEA	J:72247
Biological Process	GO:0016070	RNA metabolic process	IGI	J:23616
Biological Process	GO:0007283	spermatogenesis	IEP	J:23616
Biological Process	GO:0006369	termination of RNA polymerase II transcription	ISO	J:164563