GO Annotations Graph

• Symbol: Mylk
• Name: myosin, light polypeptide kinase
• ID: MGI:894806

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	IPI	J:166837
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004687	myosin light chain kinase activity	ISO	J:164563
Molecular Function	GO:0004687	myosin light chain kinase activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0032154	cleavage furrow	ISO	J:164563
Cellular Component	GO:0032154	cleavage furrow	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	IBA	J:265628
Biological Process	GO:0060414	aorta smooth muscle tissue morphogenesis	ISO	J:164563
Biological Process	GO:0032060	bleb assembly	ISO	J:164563
Biological Process	GO:0071476	cellular hypotonic response	ISO	J:164563
Biological Process	GO:0071277	cellular response to calcium ion	IDA	J:138635
Biological Process	GO:0035865	cellular response to potassium ion	IDA	J:138635
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	IDA	J:138635
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0051928	positive regulation of calcium ion transport	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0090303	positive regulation of wound healing	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0006939	smooth muscle contraction	IMP	J:141907
Biological Process	GO:0014820	tonic smooth muscle contraction	IMP	J:159758
Biological Process	GO:0014820	tonic smooth muscle contraction	IBA	J:265628