GO Annotations Graph

• Symbol: Dbh
• Name: dopamine beta hydroxylase
• ID: MGI:94864

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0005507	copper ion binding	ISO	J:164563
Molecular Function	GO:0005507	copper ion binding	ISO	J:155856
Molecular Function	GO:0005507	copper ion binding	IBA	J:265628
Molecular Function	GO:0004500	dopamine beta-monooxygenase activity	ISO	J:164563
Molecular Function	GO:0004500	dopamine beta-monooxygenase activity	ISO	J:155856
Molecular Function	GO:0004500	dopamine beta-monooxygenase activity	IBA	J:265628
Molecular Function	GO:0031418	L-ascorbic acid binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen	IEA	J:72247
Cellular Component	GO:0045177	apical part of cell	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0034774	secretory granule lumen	IDA	J:233593
Cellular Component	GO:0034774	secretory granule lumen	ISO	J:164563
Cellular Component	GO:0030667	secretory granule membrane	IDA	J:233593
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:164563
Cellular Component	GO:0030667	secretory granule membrane	IBA	J:265628
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Cellular Component	GO:0043196	varicosity	ISO	J:155856
Biological Process	GO:0008306	associative learning	IMP	J:41331
Biological Process	GO:0048149	behavioral response to ethanol	IMP	J:61823
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:95771
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:100317
Biological Process	GO:0042423	catecholamine biosynthetic process	IEA	J:60000
Biological Process	GO:0001816	cytokine production	IMP	J:53358
Biological Process	GO:0042420	dopamine catabolic process	ISO	J:164563
Biological Process	GO:0042420	dopamine catabolic process	IMP	J:233675
Biological Process	GO:0042420	dopamine catabolic process	IMP	J:24414
Biological Process	GO:0042420	dopamine catabolic process	IBA	J:265628
Biological Process	GO:0042420	dopamine catabolic process	IMP	J:53358
Biological Process	GO:0042596	fear response	IMP	J:89376
Biological Process	GO:0042593	glucose homeostasis	ISO	J:155856
Biological Process	GO:0042593	glucose homeostasis	IMP	J:85772
Biological Process	GO:0042309	homoiothermy	IMP	J:40052
Biological Process	GO:0002443	leukocyte mediated immunity	IMP	J:53358
Biological Process	GO:0050900	leukocyte migration	IMP	J:100317
Biological Process	GO:0007626	locomotory behavior	IMP	J:233675
Biological Process	GO:0007626	locomotory behavior	IMP	J:41331
Biological Process	GO:0042711	maternal behavior	IMP	J:44784
Biological Process	GO:0007613	memory	IMP	J:41331
Biological Process	GO:0007613	memory	IMP	J:89376
Biological Process	GO:0042421	norepinephrine biosynthetic process	IMP	J:233675
Biological Process	GO:0042421	norepinephrine biosynthetic process	IMP	J:24414
Biological Process	GO:0042421	norepinephrine biosynthetic process	ISO	J:164563
Biological Process	GO:0042421	norepinephrine biosynthetic process	ISO	J:155856
Biological Process	GO:0042421	norepinephrine biosynthetic process	IBA	J:265628
Biological Process	GO:0042421	norepinephrine biosynthetic process	IMP	J:47690
Biological Process	GO:0042421	norepinephrine biosynthetic process	IMP	J:53358
Biological Process	GO:0006589	octopamine biosynthetic process	IBA	J:265628
Biological Process	GO:0046333	octopamine metabolic process	ISO	J:155856
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:40052
Biological Process	GO:0045907	positive regulation of vasoconstriction	IMP	J:40052
Biological Process	GO:2001236	regulation of extrinsic apoptotic signaling pathway	IMP	J:100317
Biological Process	GO:1904705	regulation of vascular associated smooth muscle cell proliferation	IMP	J:100317
Biological Process	GO:1905562	regulation of vascular endothelial cell proliferation	IMP	J:100317
Biological Process	GO:0001975	response to amphetamine	IMP	J:97225
Biological Process	GO:0048265	response to pain	IMP	J:73988
Biological Process	GO:0042310	vasoconstriction	IMP	J:40052
Biological Process	GO:0008542	visual learning	IMP	J:41331