GO Annotations Graph

• Symbol: Des
• Name: desmin
• ID: MGI:94885

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:171846
Molecular Function	GO:0005515	protein binding	IPI	J:231220
Molecular Function	GO:0005515	protein binding	IPI	J:171846
Molecular Function	GO:0005515	protein binding	IPI	J:251576
Molecular Function	GO:0005515	protein binding	IPI	J:322687
Molecular Function	GO:0005515	protein binding	IPI	J:74316
Molecular Function	GO:0005200	structural constituent of cytoskeleton	TAS	J:10629
Cellular Component	GO:0097512	cardiac myofibril	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IBA	J:265628
Cellular Component	GO:0005911	cell-cell junction	IDA	J:209142
Cellular Component	GO:0043292	contractile fiber	IDA	J:87935
Cellular Component	GO:0005737	cytoplasm	IDA	J:229453
Cellular Component	GO:0005737	cytoplasm	IDA	J:170376
Cellular Component	GO:0005856	cytoskeleton	IDA	J:74316
Cellular Component	GO:0005916	fascia adherens	IDA	J:73178
Cellular Component	GO:0005921	gap junction	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	ISO	J:164563
Cellular Component	GO:0005882	intermediate filament	IDA	J:125067
Cellular Component	GO:0045111	intermediate filament cytoskeleton	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:74316
Cellular Component	GO:0005634	nucleus	IDA	J:229453
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0042383	sarcolemma	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	IDA	J:219616
Cellular Component	GO:0042383	sarcolemma	IBA	J:265628
Cellular Component	GO:0042383	sarcolemma	IDA	J:74316
Cellular Component	GO:0045098	type III intermediate filament	ISO	J:155856
Cellular Component	GO:0030018	Z disc	IDA	J:229453
Cellular Component	GO:0030018	Z disc	ISO	J:155856
Cellular Component	GO:0030018	Z disc	IBA	J:265628
Cellular Component	GO:0030018	Z disc	IDA	J:87935
Cellular Component	GO:0030018	Z disc	IDA	J:59702
Cellular Component	GO:0030018	Z disc	ISO	J:73065
Cellular Component	GO:0030018	Z disc	IDA	J:299191
Cellular Component	GO:0030018	Z disc	IDA	J:91206
Cellular Component	GO:0030018	Z disc	IDA	J:74316
Biological Process	GO:0007010	cytoskeleton organization	TAS	J:10629
Biological Process	GO:0045109	intermediate filament organization	ISO	J:164563
Biological Process	GO:0007517	muscle organ development	TAS	J:21616
Biological Process	GO:0060538	skeletal muscle organ development	IBA	J:265628