GO Annotations Graph

• Symbol: Cyb5r3
• Name: cytochrome b5 reductase 3
• ID: MGI:94893

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043531	ADP binding	ISO	J:155856
Molecular Function	GO:0016208	AMP binding	ISO	J:155856
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	ISO	J:164563
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	ISO	J:155856
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	ISO	J:73065
Molecular Function	GO:0071949	FAD binding	ISO	J:164563
Molecular Function	GO:0071949	FAD binding	ISO	J:164563
Molecular Function	GO:0071949	FAD binding	ISO	J:155856
Molecular Function	GO:0071949	FAD binding	IBA	J:265628
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	ISO	J:155856
Molecular Function	GO:0051287	NAD binding	ISO	J:155856
Molecular Function	GO:0050421	nitrite reductase (NO-forming) activity	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:304049
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:155856
Cellular Component	GO:0005811	lipid droplet	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:1903958	nitric-oxide synthase complex	ISO	J:164563
Biological Process	GO:0006695	cholesterol biosynthetic process	IEA	J:60000
Biological Process	GO:0008203	cholesterol metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0006809	nitric oxide biosynthetic process	ISO	J:164563
Biological Process	GO:0006694	steroid biosynthetic process	IEA	J:60000
Biological Process	GO:0008202	steroid metabolic process	IEA	J:60000
Biological Process	GO:0016126	sterol biosynthetic process	IEA	J:60000