GO Annotations Graph

• Symbol: Dlx2
• Name: distal-less homeobox 2
• ID: MGI:94902

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:88386
Molecular Function	GO:0003677	DNA binding	IDA	J:88386
Molecular Function	GO:0003677	DNA binding	IDA	J:44405
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:88386
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:182786
Molecular Function	GO:0005515	protein binding	IPI	J:73104
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:88386
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003727	single-stranded RNA binding	IPI	J:109093
Cellular Component	GO:0005634	nucleus	IDA	J:79854
Cellular Component	GO:0005634	nucleus	IDA	J:58233
Cellular Component	GO:0005634	nucleus	IDA	J:83565
Biological Process	GO:0048755	branching morphogenesis of a nerve	IMP	J:29443
Biological Process	GO:0051216	cartilage development	IMP	J:29443
Biological Process	GO:0051216	cartilage development	IMP	J:29443
Biological Process	GO:0051216	cartilage development	IMP	J:29443
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0021892	cerebral cortex GABAergic interneuron differentiation	IGI	J:97012
Biological Process	GO:0021892	cerebral cortex GABAergic interneuron differentiation	IGI	J:97012
Biological Process	GO:0021893	cerebral cortex GABAergic interneuron fate commitment	IGI	J:132162
Biological Process	GO:0009790	embryo development	IBA	J:265628
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	IMP	J:29443
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:40427
Biological Process	GO:0048706	embryonic skeletal system development	IGI	J:40427
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:40427
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:40427
Biological Process	GO:0048706	embryonic skeletal system development	IGI	J:40427
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:40427
Biological Process	GO:0048706	embryonic skeletal system development	IGI	J:40427
Biological Process	GO:0048706	embryonic skeletal system development	IGI	J:40427
Biological Process	GO:0021879	forebrain neuron differentiation	IGI	J:66506
Biological Process	GO:0097154	GABAergic neuron differentiation	IGI	J:66506
Biological Process	GO:0021766	hippocampus development	IGI	J:66506
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	IGI	J:196218
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	IGI	J:132162
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	IGI	J:196218
Biological Process	GO:0046533	negative regulation of photoreceptor cell differentiation	IMP	J:182786
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:132162
Biological Process	GO:0014016	neuroblast differentiation	IMP	J:79854
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:196218
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IGI	J:40427
Biological Process	GO:0021772	olfactory bulb development	IMP	J:29443
Biological Process	GO:0048709	oligodendrocyte differentiation	IGI	J:132162
Biological Process	GO:0048709	oligodendrocyte differentiation	IGI	J:196218
Biological Process	GO:0048709	oligodendrocyte differentiation	IGI	J:132162
Biological Process	GO:1902871	positive regulation of amacrine cell differentiation	IMP	J:182786
Biological Process	GO:0045597	positive regulation of cell differentiation	IMP	J:182786
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:88386
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:109093
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:109093
Biological Process	GO:0009954	proximal/distal pattern formation	IGI	J:40427
Biological Process	GO:0009954	proximal/distal pattern formation	IGI	J:40427
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:40427
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:40427
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:132162
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:188332
Biological Process	GO:0021544	subpallium development	IGI	J:196218
Biological Process	GO:0021544	subpallium development	IGI	J:196218